Results 131 to 140 of about 5,557 (173)

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

Science, 1994
Neil Stahl, Bruce A Witthuhn, Frederick W Quelle   +2 more
exaly   +2 more sources

Expression of leukemia inhibitory factor (LIF)/interleukin-6 family cytokines and receptors during in vitro osteogenesis: differential regulation by dexamethasone and LIF

Bone, 2002
Fuyou Liu, J E Aubin, Luc Malaval
exaly   +2 more sources

Are LIF and Related Cytokines Functionally Equivalent?

Experimental Cell Research, 1994
International audienceLeukemia inhibitory factor (LIF) is structurally related to interleukin-6 (IL-6), oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). Since LIF-deficient mice do not exhibit overt phenotypic effects in cell types known to be
Claire Piquet-Pellorce, John K Heath
exaly   +2 more sources

Signaling mechanisms of cytokine receptors and their perturbances in disease.

Molecular and Cellular Endocrinology, 2000
Cytokines regulate the proliferation and differentiation of cells through their interaction with specific receptors on the surface of target cells which are coupled to intracellular signal transduction pathways. The cytokine receptor class I superfamily,
I. Touw, J. Koning, A. Ward, M. Hermans
semanticscholar   +2 more sources

The family of the IL‐6‐Type cytokines: Specificity and promiscuity of the receptor complexes

Proteins: Structure, Function, and Bioinformatics, 1997
The cytokines IL-6, LIF, CNTF, OSM, IL-11, and CT-1 have been grouped into the family of IL-6-type cytokines, since they all require gp130 for signal transduction.
J. Grotzinger, G. Kurapkat, A. Wollmer, M. Kalai, S. Rose-John   +4 more
semanticscholar   +2 more sources

Receptors and signaling pathways of ciliary neurotrophic factor and the neurotrophins

, 1993
In this article, we review the receptor systems that two distinctclasses of neurotrophic factors, the neurotrophins (NGF, BDNF, NT-3 and NT-4/5) and CNTF, utilize to act on neurons. Both of these receptor systems are analogous to receptor systems outside
N. Ip, G. Yancopoulos
semanticscholar   +2 more sources

Interleukin-6 Family of Cytokines in Cancers

Journal of Interferon and Cytokine Research
Nine soluble ligands [interleukin-6 (IL-6), interleukin-11 (IL-11), leukemia inhibitory factor (LIF), oncostatin M (OSM), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, interleukin-27 (IL-27), and interleukin-31]
I. Zaporowska-Stachowiak, Michał Springer, Katarzyna Stachowiak, M. Oduah, Maciej Sopata, K. Wieczorowska-Tobis, W. Bryl   +6 more
semanticscholar   +1 more source

Leukemia inhibitory factor (LIF) and oncastsin M (OSM) high affinity binding require additional receptor subunits besides GP130 and GP190.

Cytokine, 1996
D. Heymann, A. Godard, S. Raher, N. Bentouimou, F. Blanchard, M. Chérel, M. Hallet, Y. Jacques   +7 more
semanticscholar   +1 more source

The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor.

Science, 1992
D. Gearing, Comeau, DJ Friend, S. Gimpel, C. Thut, J. McGourty, KK Brasher, J. King, S. Gillis, B. Mosley   +9 more
semanticscholar   +1 more source

Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit.

Blood, 1999
Minoru Tanaka, Takahiko Hara, N. G. Copeland, D. J. Gilbert, N. Jenkins, Atsushi Miyajima   +5 more
semanticscholar   +1 more source