Results 221 to 230 of about 2,381,066 (350)

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

Experimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela, Anuja R. Bony, Sonia Garcia‐Caraballo, David J. Adams, Stuart M. Brierley   +4 more
wiley   +1 more source

Oxytocin Deficiency in Childhood and Adolescence: Clinical Features, Diagnostic Challenges and Therapeutic Perspectives. [PDF]

Curr Issues Mol Biol
Paparella R, Bei A, Bernabei I, Fiorentini C, Iafrate N, Lucibello R, Marchetti L, Pastore F, Maglione V, Niceta M, Fiore M, Caronti B, Vitali M, Pucarelli I, Tarani L.   +14 more
europepmc   +1 more source

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

The Journal of Physiology, EarlyView.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

An overview of oxytocin integrative mechanisms in autism spectrum disorder. [PDF]

Discov Ment Health
Lal N, Song B, Zhang C, Al-Shehari WA, Jabeen S, Ahmed N, Edrees WH, Gupta R, Soomro S, Cui F, Qasem EA.   +10 more
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Oxytocin administration during labor does not affect maternal serum oxytocin levels, early postpartum breastfeeding attitude and maternal attachment. [PDF]

PLoS One
Özdemir M, Çeber Turfan E, Keskin HL.
europepmc   +1 more source

Oxytocin Receptor Expression and Activation in Parasympathetic Brainstem Cardiac Vagal Neurons. [PDF]

eNeuro
Wang X, Ribeiro C, Nilsson A, Escobar JB, Alber BR, Bethea JR, Polotsky VY, Kay MW, Schunke K, Mendelowitz D.   +9 more
europepmc   +1 more source

Quantitative Determination and Stability of Trace Levels of Oxytocin in Human and Rhesus Macaque Urine by LC–MS/MS

Biomedical Chromatography, Volume 40, Issue 3, March 2026.
ABSTRACT Oxytocin (OT) quantification in biological samples is vital for understanding its role in social behavior, emotion, and brain development in humans and animals. Urinary OT analysis has gained attention but is challenging due to variability in matrix effects, background interference, low concentrations, and stability concerns.
Xing Zhang, Lori Fralick, Kelly Ethun
wiley   +1 more source

Precocial Weaning Influences Anxiety, Social and Maternal Care but Not Cognition in African Striped Mice, Rhabdomys dilectus chakae

Developmental Psychobiology, Volume 68, Issue 2, March 2026.
ABSTRACT Weaning is a stressful stage in the lives of young mammals. Early weaning, in particular, can lead to long‐lasting physiological and psychological changes. We investigated the effects of precocial weaning on anxiety, social behavior, cognition, and maternal behavior in adult African four‐striped mice (Rhabdomys dilectus chakae). Mice weaned at
Maria K Oosthuizen, Neville Pillay
wiley   +1 more source

Early Life Mild Adversity Affects in a Sexually Dimorphic Way the Oxytocinergic System Reducing Close Social Interaction in Adult Male Rats. [PDF]

J Neurochem
Raftogianni A, Pavlidi L, Galeou S, Kalpachidou T, Stylianopoulou F, Stamatakis A.   +5 more
europepmc   +1 more source