Results 291 to 300 of about 2,381,066 (350)
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Hormonal influences in migraine — interactions of oestrogen, oxytocin and CGRP
Nature Reviews Neurology, 2021Diana N Krause +2 more
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Trends in Endocrinology & Metabolism, 2003
Novel sites of oxytocin receptor expression have recently been detected, including breast cancer cells, bone cells, myoblasts, cardiomyocytes and endothelial cells. These discoveries have greatly expanded the possible spectrum of oxytocin action beyond its classic role as an inducer of uterine contractions and milk ejection.
Hans H, Zingg, Stephane A, Laporte
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Novel sites of oxytocin receptor expression have recently been detected, including breast cancer cells, bone cells, myoblasts, cardiomyocytes and endothelial cells. These discoveries have greatly expanded the possible spectrum of oxytocin action beyond its classic role as an inducer of uterine contractions and milk ejection.
Hans H, Zingg, Stephane A, Laporte
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Regulation of Oxytocin Receptors and Oxytocin Receptor Signaling
Seminars in Reproductive Medicine, 2007The oxytocin (OT) -oxytocin receptor (OTR) system plays a key role in many aspects of mammalian reproduction as well as several other physiological processes such as bond pairing and cardiovascular homeostasis. To manifest these diverse physiological roles, the transcription and expression of the OTR is tightly regulated within reproductive ...
Andrew M, Blanks +2 more
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Oxytocin Receptor Antagonists: Update
Clinics in Perinatology, 1998For over three decades, scientists in a number of different laboratories have worked to design peptide analogues of oxytocin (OT) selective for the oxytocin receptor. Although there has been some interest in their use for treatment of dysmenorrhea, the principal clinical venue for such agents has been thought to lie in treatment of preterm labor.
T M, Goodwin, A, Zograbyan
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Oxytocin-induced desensitization of the oxytocin receptor
American Journal of Obstetrics and Gynecology, 2003The purpose of this study was to characterize the oxytocin-induced desensitization of oxytocin-stimulated rises of intracellular calcium in cultured human myocytes.Culture lines were begun from biopsy specimens of myometrium that had been obtained from women who underwent low transverse cesarean deliveries.
Christopher, Robinson +3 more
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A ghrelin receptor and oxytocin receptor heterocomplex impairs oxytocin mediated signalling
Neuropharmacology, 2019Oxytocin mediates its behavioural effects via the centrally expressed oxytocin receptor (OTR). Oxytocin signalling has been implicated in multiple disorders involving centrally regulated pathways, including obesity, autism, schizophrenia and depression.
Shauna E. Wallace Fitzsimons +7 more
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2008
The great diversity of the expression sites and proposed function of the oxytocin (OXT) receptor (OXTR) is paralleled by a diversity of its signalling pathways, many of which have still remained unexplored. We have used different approaches to discover novel pathways.
Dominic, Devost +2 more
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The great diversity of the expression sites and proposed function of the oxytocin (OXT) receptor (OXTR) is paralleled by a diversity of its signalling pathways, many of which have still remained unexplored. We have used different approaches to discover novel pathways.
Dominic, Devost +2 more
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1999
The oxytocin receptor was first identified using a pharmacological ligandbinding assay in the rat myometrium (Soloff and Swartz 1973). Its peptide ligand, oxytocin, belongs to the nonapeptide hormone family comprising both oxytocin-like (mesotocin, isotocin, etc.) and vasopressin-like (vasotocin, phenypressin, etc.) cyclic peptides.
T, Kimura, R, Ivell
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The oxytocin receptor was first identified using a pharmacological ligandbinding assay in the rat myometrium (Soloff and Swartz 1973). Its peptide ligand, oxytocin, belongs to the nonapeptide hormone family comprising both oxytocin-like (mesotocin, isotocin, etc.) and vasopressin-like (vasotocin, phenypressin, etc.) cyclic peptides.
T, Kimura, R, Ivell
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Vasopressin and oxytocin receptors
Baillière's Clinical Endocrinology and Metabolism, 1996The oxytocin and the vasopressin V1a, V1b and V2 receptors have recently been cloned and shown to form a sub-family within the large superfamily of G-protein-linked receptors. Renal V2 receptors mediate vasopressin-induced water reabsorption via induction of intracellular cAMP production in collecting duct cells.
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Oxytocin and Oxytocin Receptors in Cancer Cells and Proliferation
Journal of Neuroendocrinology, 2004AbstractThe hypothalamic nonapeptide oxytocin plays a crucial role in many reproductive and behavioural functions. However, in recent years, an additional new role for oxytocin has been identified in neoplastic pathology. In tumours, oxytocin acts as a growth regulator, through the activation of a specific G‐coupled transmembrane receptor, the oxytocin
CASSONI, Paola +4 more
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