Results 171 to 180 of about 95,091 (211)
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Progesterone Receptors in Rat Thymus
Endocrinology, 1983Tritiated promegestone ([3H]R5020) is bound with high affinity in cytosol prepared from the thymus gland of both male and female rats. To prevent tracer binding to glucocorticoid receptors, we have used excess RU26988 (11 beta, 17 beta-dihydroxy-21-methyl-17 alpha-pregna-1,4,6-trien-20-yn-3-one), a highly specific synthetic glucocorticoid.
P T, Pearce, B A, Khalid, J W, Funder
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Activation of Progesterone Receptor by ATP
European Journal of Biochemistry, 1981Progesterone-receptor complex from freshly prepared hen oviduct cytosol acquired the ability to bind to isolated nuclei, DNA-cellulose and ATP-Sepharose when incubated with 5-10 mM ATP at 4 degrees C. The extent of this ATP-dependent activation was higher when compared with heat-activation achieved by warming the progesterone-receptor complex at 23 ...
V, Moudgil +5 more
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Progesterone and the progesterone receptor.
The Journal of reproductive medicine, 2001During the 1990s, extensive research has effectively mapped the progesterone receptor-mediated actions of progesterone and has more recently uncovered nonreceptor-mediated effects--the effect of progesterone on uterine sensitivity to oxytocin, for example, involves direct, nongenomic progesterone action on the uterine oxytocin receptor.
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Progesterone receptors in breast fibroadenomas
Journal of Steroid Biochemistry, 1979Abstract Cytosol progesterone receptors (P-R) were measured in breast fibroadenomas from 88 women, and their levels were compared to the tumor epithelial cell density and estradiol receptor levels (E-R). Three groups of fibroadenoma were distinguished: type I with a high epithelial cell density (n= 18), type III (n = 46) with low epithelial cell ...
P M, Martin +3 more
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Progesterone Receptor Interaction with Chromatin
2014Understanding how eukaryotic gene regulation works implies unraveling the mechanisms used by transcription factors to access DNA information packaged in chromatin. The current view is that different cell types express different parts of the genome because they are equipped with different sets of transcription factors.
Guillermo P, Vicent +5 more
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Estrogen and progesterone receptors in meningiomas
Journal of Neurosurgery, 1984✓ Two-thirds of all meningiomas and four-fifths of intraspinal and sphenoidal meningiomas occur in women. Meningiomas frequently enlarge or become symptomatic during pregnancy or during the luteal phase of the menstrual cycle. There is an increased incidence of meningiomas in women with breast carcinoma. In a series of 23 patients with meningiomas, the
D W, Cahill +5 more
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Structural analyses of progesterone receptors
Journal of Steroid Biochemistry, 1986Progesterone receptors of T47Dco human breast cancer cells consist of two equimolar hormone-binding proteins of mol. wt approximately 85,000 (A protein) and 115,000 (B protein). Both proteins can be demonstrated in intact cells by in situ photoaffinity labeling; that is, in cells treated with the synthetic progestin [3H]R5020, irradiated 2 min with 300
K B, Horwitz, L L, Wei, M D, Francis
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Progesterone Receptor in Cystosarcoma Phyllodes
Archives of Surgery, 1977A specific receptor for progesterone has been found in a cystosarcoma phyllodes, as determined by charcoal adsorption and sucrose gradient analysis. Similar assays for estrogen receptors were negative. The tumor consisted almost entirely of stroma that contained the progesterone receptors.
B R, Rao, J S, Meyer
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PROGESTERONE RECEPTORS IN BREAST CANCER
Australian and New Zealand Journal of Surgery, 1984Sixty‐six women who had received hormonal therapy for advanced disease were assessed for objective response to treatment. Another 51 patients who had received chemotherapy were similarly studied. Progesterone receptor was of no value as a predictor of patients unlikely to respond to hormone therapy, though it may have a role in predicting patients ...
R M, Bryan +5 more
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Journal of Steroid Biochemistry, 1979
Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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