Results 71 to 80 of about 684,032 (303)

Progesterone for the prevention of preterm birth in twin pregnancy (STOPPIT) : a randomized, double-blind, placebo-controlled study and meta-analysis EDITORIAL COMMENT [PDF]

, 2009
Women with twin pregnancy are at high risk of spontaneous preterm delivery. Three large randomized trials have shown that progesterone reduces the rate of preterm delivery in high-risk singleton pregnancies, although evidence of significant reduction in ...
Thornton, J.G., Thornton, James G., Thornton, Steven, Mires, Gary, Tydeman, Graham, Norman, Jane E., MacTier, H., Cooper, Sarah, Mactier, Helen, Martin, B., Norman, Jane E, Sturgiss, Stephen, MacKenzie, F., Mackenzie, Fiona, MacLennan, Graeme, Neilson, J.P., Danielian, P., Mires, G., Owen, Philip, Hanretty, Kevin, Calder, Andrew, Neilson, James P., Tydeman, G., Calder, A., Thornton, S., Thornton, James G, Danielian, Peter, Norman, J.E., Hanretty, K., Neilson, James P, Martin, Bill, Cooper, S., Norrie, J., Owen, P., Sturgiss, S., MacLennan, G., Norrie, John   +36 more
core   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Progesterone action in the myometrium and decidua in preterm birth [PDF]

, 2012
Progesterone is central to many reproductive processes and is critical in regulating the menstrual cycle and maintaining pregnancy. We discuss here similarities in the molecular mechanisms that regulate the process of decidualisation in endometrial ...
Blanks, Andrew M., Brosens, Jan J.
core  

Progesterone: A Neuroprotective Steroid of the Intestine

, 2023
The enteric nervous system (ENS) is an intrinsic network of neuronal ganglia in the intestinal tube with about 100 million neurons located in the myenteric plexus and submucosal plexus.
Sarah Stahlke, Lennart Norman Stegemann, Carsten Theiss, Paula Maria Neufeld, Ines Hecking, Matthias Vorgerd, Veronika Matschke   +6 more
core   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

ROLE OF ANTIPROGESTERONE ON THE ENDOMETRIUM RECEPTIVITY- A REVIEW

Pakistan Armed Forces Medical Journal, 2016
Estrogen produces proliferation in the functional layer of the endometrium and the differentiation in theciliated and secretory epithelium of the uterine tube.
Khadija Qamar, Rubina Mushtaq, Humaira Arshad   +2 more
doaj   +2 more sources

A Study of Hormonal Receptors in Esophageal Carcinoma: Northeast Indian Tertiary Cancer Center Study

South Asian Journal of Cancer, 2020
Background Esophageal cancers, both squamous cell and adenocarcinoma, have poor outcomes with high morbidity and mortality. Our hospital-based registry for the year 2017 to 2018 showed that esophageal cancer constituted 22.7% of annual caseload.
Deepjyoti Kalita, Srinivas Bannoth, Joydeep Purkayastha, Abhijit Talukdar, Gaurav Das, Pritesh Singh   +5 more
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

An approach to malignant mammary phyllodes tumors detection [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. Mammary phyllodes tumors (MPT) are uncommon fibroepithelial (biphasic) neoplasms whose clinical behavior is difficult to predict on the basis of histological criteria only.
Ilić Ivan, Ranđelović Pavle, Ilić Ratko, Katić Vuka, Milentijević Maja, Veličković Ljubinka, Krstić Miljan   +6 more
doaj   +1 more source

Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]

, 1992
We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J., Sterzik, K., Gratzl, Manfred, Mayerhofer, Artur   +3 more
core   +1 more source