Role of Prolactin Receptors in Lymphangioleiomyomatosis. [PDF]
PLoS ONE, 2016 Pulmonary lymphangioleiomyomatosis (LAM) is a rare lung disease caused by mutations in the tumor suppressor genes encoding Tuberous Sclerosis Complex (TSC) 1 and TSC2.
Amira Alkharusi +6 more
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Prolactin and the prolactin receptor: new targets of an old hormone
Annals of Medicine, 2004 Prolactin (PRL) is one of a family of related hormones including growth hormone (GH) and placental lactogen (PL) that are hypothesized to have arisen from a common ancestral gene about 500 million years ago. Over 300 different functions of PRL have been reported, highlighting the importance of this pituitary hormone. PRL is also synthesized by a number
Christopher Ormandy +2 more
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Use of acupuncture to reduce prolactin levels in antipsychotically induced hyperprolactinemia: a case report [PDF]
Frontiers in MedicineIntroductionHyperprolactinemia, an endocrine disorder, has witnessed a notable increase in incidence in recent years, exerting a substantial influence on patients’ physiological states and quality of life.
Qi Wang +5 more
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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models [PDF]
The Journal of Headache and PainBackground Migraine impacts 15% of the global population, predominantly women. Previous studies have shown a role for prolactin in animal migraine models induced by either stimulation of the dura mater or repeated stress exposure.
Hao-Ruei Mei +9 more
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The brain as a source and a target of prolactin in mammals
Neural Regeneration Research, 2022 Prolactin is a polypeptide hormone associated with an extensive variety of biological functions. Among the roles of prolactin in vertebrates, some were preserved throughout evolution.
Ana R Costa-Brito +2 more
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Secretion and Function of Pituitary Prolactin in Evolutionary Perspective
Frontiers in Neuroscience, 2020 The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient vertebrate hormone released from the pituitary that exerts particularly diverse functions.
Arpád Dobolyi +8 more
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Differential gene expression in patients with anal fistula reveals high levels of prolactin recepetor [PDF]
Vojnosanitetski Pregled, 2017 Background/Aim. There are limited data examining variations in the local expression of inflammatory mediators in anal fistulas where it is anticipated that an improved understanding of the inflammatory milieu might lead to the potential therapeutic ...
Song Yi-Huan +5 more
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Prolactin receptors and placental lactogen drive male mouse pancreatic islets to pregnancy-related mRNA changes. [PDF]
PLoS ONE, 2015 Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets.
Lotte Goyvaerts +9 more
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Prolactin and oxytocin: potential targets for migraine treatment
The Journal of Headache and Pain, 2023 Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully understood. Besides the role of inflammatory mediators that interact with the trigeminovascular system, cyclic fluctuations in sex steroid hormones are involved in ...
Anna K. Szewczyk +18 more
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Animals, 2020 Reproduction in vertebrates is controlled by the hypothalamo-pituitary-gonadal axis, and both the sex steroid and pituitary hormones play a pivotal role in the regulation of the physiology of the oviduct and events occurring within the oviduct.
Claire Brun +2 more
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