Results 101 to 110 of about 2,570,395 (251)

Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells

Cell Reports, 2016
In the pancreatic islet, serotonin is an autocrine signal increasing beta cell mass during metabolic challenges such as those associated with pregnancy or high-fat diet.
Joana Almaça, Judith Molina, Danusa Menegaz, Alexey N. Pronin, Alejandro Tamayo, Vladlen Slepak, Per-Olof Berggren, Alejandro Caicedo   +7 more
doaj   +1 more source

A High-Resolution In Vivo Atlas of the Human Brain's Serotonin System

Journal of Neuroscience, 2017
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain functions and is critically involved in many neuropsychiatric disorders. Here, we present a high-resolution, multidimensional, in vivo atlas of four of the human brain's 5-HT
V. Beliveau, M. Ganz, Ling Feng, B. Ozenne, L. Højgaard, P. Fisher, C. Svarer, D. Greve, G. Knudsen   +8 more
semanticscholar   +1 more source

The Effects of Epigenetics on Stress Response [PDF]

, 2016
Despite the vast amount of resources at the disposal of humanity today, the intricacies of human biology are often a mystery. The chemical and biological products of the human genome have been well studied and documented, but many of the chemical and ...
Suddarth, Kevin
core   +1 more source

Sustained Exposure to 3,4-Methylenedioxymethamphetamine Induces the Augmentation of Exocytotic Serotonin Release in Rat Organotypic Raphe Slice Cultures

Journal of Pharmacological Sciences, 2010
3,4-Methylenedioxymethamphetamine (MDMA) causes serotonin efflux via serotonin transporter. Recently, we have reported that sustained exposure to MDMA induced an augmentation of serotonin release in rat raphe serotonergic slice cultures.
Kazuki Nagayasu, Maiko Kitaichi, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko   +4 more
doaj   +1 more source

Structure, dynamics and lipid interactions of serotonin receptors: excitements and challenges

Biophysical Reviews, 2020
P. Sarkar, Sukanya Mozumder, Aritra Bej, Sujoy Mukherjee, J. Sengupta, A. Chattopadhyay   +5 more
semanticscholar   +1 more source

Experimental approaches to understanding the role of protein phosphorylation in the regulation of neuronal function [PDF]

, 1983
Studies by Earl Sutherland and his colleagues on hormonal regulation of the breakdown of glycogen in liver resulted in the discovery that the first step in the action of many hormones is to increase the synthesis of cAMP by activating adenylate cyclase ...
Kennedy, Mary B.
core  

Serotonin and psilocybin activate 5-HT1B receptors to suppress cortical signaling through the claustrum

Nature Communications
Through its widespread reciprocal connections with the cerebral cortex, the claustrum is implicated in sleep and waking cortical network states. Yet, basic knowledge of neuromodulation in this structure is lacking.
Maxwell B. Madden, Chloe Schaefgen, Binita Vedak, Jian Kwon, Kiara S. Dresp Pedra, Samuel H. Sheats, Adam C. Puche, Steffen B. E. Wolff, Brian N. Mathur   +8 more
doaj   +1 more source

The Effect of Serotonin on Leptin and Grelin Hormones Concentrations in Female Rats

Kufa Journal for Veterinary Medical Sciences, 2015
This study was aimed to investigate the relationship of hyperserotoninemia on the adipose tissues performance and satiety status on thirty six female rats. Randomly divided into four groups that individually housed.
Noaman I. M
doaj   +1 more source

Serotoninergic regulation of colonic motor function

Терапевтический архив, 2013
The review deals with the serotoninergic regulation of colonic motor function. Serotonin (HT), its receptors and transporter, the enzymes of synthesis and degradation, play an important role in the regulation of colonic motor activity.
A É Lychkova
doaj  

Heteroreceptor complexes and their allosteric receptor-receptor interactions in the central nervous system. Focus on examples from Dopamine D2 and Serotonin 5-HT1a receptors [PDF]

, 2018
GPCR interacting proteins (specially β- arrestin) and their receptor-protein interactions are also covered but their interactions with the allosteric receptor-receptor interactions in heteroreceptor complexes remain to be elucidated.
Corrales Ferro, Fidel
core   +1 more source