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Serotonin 2A receptors and cannabinoids
2021Accumulating evidence has proven that both exogenous cannabinoids as well as imbalances in the endocannabinoid system are involved in the onset and development of mental disorders such as anxiety, depression, or schizophrenia. Extensive recent research in this topic has mainly focused on the molecular mechanisms by which cannabinoid agonists may ...
Inés Ibarra-Lecue +2 more
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Drugs affecting serotonin receptors
Baillière's Clinical Gastroenterology, 1994A greater understanding of the various serotonin receptor subtypes has led to a clearer appreciation of the role of serotonin in gastrointestinal motility, sensation and secretion. Serotonin is definitely involved in the aetiopathogenesis of cisplatin-induced emesis and carcinoid diarrhoea. The application of serotonergic drugs in clinical therapeutics
Manfred R. Von Der Ohe +1 more
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Molecular Biology Of Serotonin Receptors
Annual Review of Neuroscience, 1991Serotonin (S-hydroxytryptamine; SHT) is a biogenic amine that functions as both a neurotransmitter and a hormone in the mammalian central nervous system (CNS) and in the periphery. Within the brain, serotonergic neurons originate primarily in the raphe nuclei of the brainstem and project to most areas of the CNS, where they regulate a wide variety of ...
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Serotonin Receptors and Neurotransmission
2004Publisher Summary This chapter focuses on neurotransmission and serotonin receptors, their synthesis, and metabolism. Serotonin (5-HT) is a neurotransmitter as well as a circulating hormone. Serotoninergic neurons in the brain synthesize and store serotonin at axon terminals where it is released and interacts with cell-surface receptors on adjacent ...
Elaine Sanders-Bush, Charles D. Nichols
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Receptors | Serotonin Receptor Signaling
Encyclopedia of Biological Chemistry III, 2021P. Gresch, Vivian Kitainda
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Structural insights into the lipid and ligand regulation of serotonin receptors
Nature, 2021P. Xu +18 more
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1984
With the catecholamines (dopamine, norepinephrine, and epinephrine), serotonin (5-HT, 5-hydroxytryptamine) is one of the best known biogenic amine neurotransmitters in the CNS. During the past 20 years, an abundant literature has been devoted to this molecule, exploring its distribution, metabolism, and functions.
Michel Hamon +3 more
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With the catecholamines (dopamine, norepinephrine, and epinephrine), serotonin (5-HT, 5-hydroxytryptamine) is one of the best known biogenic amine neurotransmitters in the CNS. During the past 20 years, an abundant literature has been devoted to this molecule, exploring its distribution, metabolism, and functions.
Michel Hamon +3 more
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Dissecting Serotonin Receptors
Science Signaling, 2013Structures of serotonin receptor family members in complex with the fungal alkaloid ergot offer clues for drug designers.
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Serotonin induces melanogenesis via serotonin receptor 2A
British Journal of Dermatology, 2011Serotonin (5-hydroxytryptamine, 5-HT) levels are increased by light exposure but the role and mechanism of 5-HT in the pigmentation of skin cells are unclear.To clarify the effect of 5-HT on melanogenesis and to determine the 5-HT receptor subtype involved.B16F10, SK-MEL-2 and Melan-A cells were cultured in Dulbecco's modified Eagle's medium with low ...
H.J. Lee +5 more
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Serotonin receptor sensitivity and aggression
Psychiatry Research, 1991This study investigated the relationship between increased serotonin (5-hydroxytryptamine, 5HT) receptor sensitivity and human aggression. A low oral dose of meta-chlorophenylpiperazine (MCPP), a postsynaptic 5HT receptor agonist, was administered in a placebo-controlled design to depressed (n = 22) and panic disorder (n = 20) patients classified with ...
R.S. Kahn +4 more
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