The role of peripheral serotonin in SARS-CoV-2 infectivity, COVID-19 treatment and long COVID. [PDF]
Thorpe DW +6 more
europepmc +1 more source
The multiple hit model of infantile and epileptic spasms: The 2025 update
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Serotonin Associated Mechanisms in Sudden Unexpected Death in Epilepsy: A Review. [PDF]
Li B +6 more
europepmc +1 more source
Ketogenic diet for infantile epileptic spasms
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Updated Viloxazine Pharmacology: Experiments Establish Norepinephrine Transporter Occupancy and Serotonin 5-HT<sub>2C</sub>, 5-HT<sub>2B</sub>, and 5-HT<sub>7</sub> Receptor Binding at Therapeutically Relevant Concentrations. [PDF]
Garcia-Olivares J +4 more
europepmc +1 more source
An iEEG investigation on sex‐specific differences in seizure duration
Abstract Objective Male people with epilepsy (mPWE) are at higher risk for bilateral tonic–clonic seizures (BTCs) and sudden unexpected death in epilepsy (SUDEP) compared to female people with epilepsy (fPWE). Despite major clinical and personal implications, little is known about sex‐specific differences in seizure propagation and termination ...
Paula Albert I Gracenea +4 more
wiley +1 more source
Differential Autoregulation of Serotonin Secretion at Different Structures of Serotonergic Neurons. [PDF]
Trueta C, Cercós MG.
europepmc +1 more source
ABSTRACT Objective The early response effect, defined as a reliable symptomatic improvement during the initial phase of treatment, is the most robust predictor of recovery following eating disorder treatment. This study aimed to investigate which symptom domains mostly influence the early response effect. Methods Data from N = 232 adult patients (90.8%
Ammara Imtiaz +3 more
wiley +1 more source
Dopamine's secret agent: serotonin. [PDF]
Miller-Hansen AJ, Lerner TN.
europepmc +1 more source
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique +6 more
wiley +1 more source

