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5-HT Receptors and Temperature Homeostasis [PDF]
Biomolecules, 2021 The present review summarizes the data concerning the influence of serotonin (5-HT) receptors on body temperature in warm-blooded animals and on processes associated with its maintenance.
Irina P. Voronova
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Comparative analysis of palmitoylation sites of serotonin (5‐HT) receptors in vertebrates [PDF]
Neuropsychopharmacology Reports, 2018 Background In the vertebrate central nervous system as well as in the periphery, serotonin, also known as 5‐hydroxytriptamine (5‐HT), function as a neurotransmitter, a hormone or a mitogen.
Toshie Kaizuka, Takashi Hayashi
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The role of 5-HT receptors in depression [PDF]
Molecular Brain, 2017 Depression is a polygenic and highly complex psychiatric disorder that remains a major burden on society. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are some of the most commonly prescribed drugs worldwide.
Christine N. Yohn +2 more
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Natural Negative Allosteric Modulators of 5-HT3 Receptors [PDF]
Molecules, 2018 Chemotherapy-induced nausea and vomiting (CINV) remain the most common and devastating side-effects associated with cancer chemotherapy. In recent decades, several lines of research emphasize the importance of 5-hydroxytryptamine3 (5-HT3; serotonin ...
Lina T. Al Kury +3 more
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Serotonin signaling modulates growth and motility in juvenile Fasciola hepatica. [PDF]
PLoS Neglected Tropical DiseasesFasciola hepatica causes fasciolosis, a parasitic disease that poses significant animal and human health challenges. Control relies on flukicides, most of which are adulticides, with only triclabendazole effective against the pathogenic migratory ...
Emily Robb +10 more
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Serotonergic modulation of excitatory synapse development and plasticity [PDF]
Molecules and Cells: Excitatory synapse plasticity at postsynaptic dendritic spines is directly modulated through neurotransmitter signaling. Serotonin (5-HT) is a primary neuromodulator in the brain that activates 14 subtypes of G-protein-coupled receptors, each with ...
Victoria N. Chang +3 more
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Can Serotonin 7 Receptors Be a Treatment Target for Noncentral Diseases?
Eurasian Journal of Medicine, 2023 The neurotransmitter serotonin (5-HT) is involved in several key processes in the central nervous system. But the great majority of serotonin is produced by intestinal enterochromafn cells of the gastrointestinal (GI) tract and circulating blood ...
Aslı Özbek Bilgin
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5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability
iScience, 2023 Summary: Many psychiatric diseases have been associated with serotonin (5-HT) neuron dysfunction. The firing of 5-HT neurons is known to be under 5-HT1A receptor-mediated autoinhibition, but functional consequences of coexpressed receptors are unknown ...
Amina Benhadda +8 more
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Serotonin receptors as cardiovascular targets [PDF]
, 1997 Serotonin exerts complex effects in the cardiovascular system, including hypotension or hypertension, vasodilatation or vasoconstriction, and/or bradycardia or tachycardia; the eventual response depends primarily on the nature of the 5-HT receptors ...
Saxena, P.R. (Pramod Ranjan) +2 more
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Multiple modulatory roles of serotonin in chronic pain and injury-related anxiety
Frontiers in Synaptic Neuroscience, 2023 Chronic pain is long-lasting pain that often persists during chronic diseases or after recovery from disease or injury. It often causes serious side effects, such as insomnia, anxiety, or depression which negatively impacts the patient’s overall quality ...
Shun Hao +11 more
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