Results 251 to 260 of about 197,813 (313)

Tryptamine and Serotonin Receptors

Nature, 1962
A RECENT communication by Vane et al. entitled “Tryptamine Receptors in the Central Nervous System”1 concluded, on the basis of indirect evidence, that the receptors for tryptamine and for serotonin (5-hydroxytryptamine) were the same. Because the authors neglected to mention some earlier evidence of a more direct kind which showed clearly that certain
D W, WOOLLEY, E, SHAW
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Palmitoylation of serotonin receptors

Biochemical Society Transactions, 2013
The covalent attachment of palmitic acid to one or more cysteine residues (S-palmitoylation) is a widespread modification of signalling proteins. With the finding that palmitoylation is a dynamic process, it is now widely accepted that repeated cycles of palmitoylation/depalmitoylation could be involved in the regulation of multiple signalling ...
Nataliya, Gorinski, Evgeni, Ponimaskin
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Subtypes of Receptors for Serotonin

Annual Review of Pharmacology and Toxicology, 1990
Interest in the physiological functions of 5-hydroxytryptamine (5-HT; seroto­ nin) has increased steadily since its discovery in the intestine (1) and in serum (2). Its identification in brain in the early 1950s (3), followed a decade later by the initial studies of its distribution in brain by histofluorescence (4), stimulated investigations of the ...
A, Frazer, S, Maayani, B B, Wolfe
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Serotonin Transporter and Serotonin Receptors

2013
The nature of the primary defect responsible for triggering and maintaining pulmonary artery smooth muscle (PA-SMC) proliferation in pulmonary artery hypertension (PAH) is poorly understood but may be either an inherent characteristic of PA-SMCs or a secondary response to an external abnormality, such as upregulation of growth factors.
Serge, Adnot, Amal, Houssaini, Shariq, Abid, Elisabeth, Marcos, Valérie, Amsellem   +4 more
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Serotonin Receptor Subtypes

1993
The fact that nearly all known serotonin receptor subtypes are single subunit proteins, members of the same gene superfamily (the G protein-coupled receptor or 7TM superfamily) and that most are intronless genes has helped accelerate the cloning of this receptor family.
P R, Hartig, N, Adham, J, Zgombick, M, Macchi, H T, Kao, L, Schechter, T, Branchek, R, Weinshank   +7 more
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Serotonin and serotonin receptors in the central auditory system

Otolaryngology–Head and Neck Surgery, 1994
Immunohistochemical and ligand‐binding techniques were used to visualize the neurotransmitter serotonin and one of its receptors, the 5‐HT1A subtype, in auditory nuclei of the brainstem. Serotonergic fibers and terminal endings were found in all auditory nuclei extending from the cochlear nucleus to the inferior colliculus, including the superior ...
G C, Thompson, A M, Thompson, K M, Garrett, B H, Britton   +3 more
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Serotonin receptors

2002
Abstract The pharmacology of serotonin (5-hydroxytryptamine; 5-HT) was reviewed in 1986 (Bradley et al .) acknowledging the existence of at least three 5-HT receptor families: 5-HT1–3. In the 15 years following this classification molecular cloning has confirmed the existence of multiple 5-HT receptors subtypes.
Claire Roberts, Gary W Price, Derek N Middlemiss   +2 more
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Serotonin receptor sensitivity and aggression

Psychiatry Research, 1991
This study investigated the relationship between increased serotonin (5-hydroxytryptamine, 5HT) receptor sensitivity and human aggression. A low oral dose of meta-chlorophenylpiperazine (MCPP), a postsynaptic 5HT receptor agonist, was administered in a placebo-controlled design to depressed (n = 22) and panic disorder (n = 20) patients classified with ...
S, Wetzler, R S, Kahn, G M, Asnis, M, Korn, H M, van Praag   +4 more
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