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Serotonin Receptors in Rat Lung

Respiration, 1986
Mammalian lungs have been shown to store and to inactivate serotonin by an active process involving uptake and metabolism. Serotonin has direct action on lung including constrictor effects of pulmonary vascular and tracheobronchial smooth muscle suggesting the presence of serotonin receptors in lung.
D K, Das, H, Steinberg
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Molecular Biology Of Serotonin Receptors

Annual Review of Neuroscience, 1991
Serotonin (S-hydroxytryptamine; SHT) is a biogenic amine that functions as both a neurotransmitter and a hormone in the mammalian central nervous system (CNS) and in the periphery. Within the brain, serotonergic neurons originate primarily in the raphe nuclei of the brainstem and project to most areas of the CNS, where they regulate a wide variety of ...
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Oligomerization of Dopamine and Serotonin Receptors

Neuropsychopharmacology, 2000
Until recently, it has largely been assumed that G protein-coupled receptors (GPCRs) function as monomeric entities. However, over the past few years, we and others have documented that GPCRs can form dimers and oligomers, leading to a re-evaluation of the mechanisms thought to mediate GPCR function.
S P, Lee   +5 more
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Serotonin and Serotonin Receptors in Hallucinogen Action

2010
Abstract Hallucinogens (psychedelics) are substances that induce profound changes in perception and cognition. The closely related 3,4-methylenedioxymethamphetamine (MDMA) produces euphoria and a feeling of empathy, with minimal sensory distortion. Both of these classes of substances produce their effects by interacting with the serotonergic system ...
Adam L. Halberstadt, David E. Nichols
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Serotonin receptors: Clinical implications

Neuroscience & Biobehavioral Reviews, 1990
Over the past decade, a variety of serotonin (5-hydroxytryptamine, 5-HT) receptor/binding sites have been identified. These include 5-HT1, 5-HT2, and 5-HT3 sites. The 5-HT1 sites have been further divided into 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT1E sites.
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Serotonin Receptors

Chemical Reviews, 2008
David E, Nichols, Charles D, Nichols
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Serotonin receptors-where are they going?

International Clinical Psychopharmacology, 1994
Thirty-three years ago, Gaddum and Picarelli classified the serotonin (5-HT) receptors in the guinea-pig ileum into D and M types based on the activity of dibenzyline (D) and morphine (M) to block contractions of intestinal smooth muscles caused by 5-HT.
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Serotonin receptors in brain revisited

Brain Research, 2016
In the early 1980's, the dispute on the existence of a multiplicity of receptors for neurotransmitter was at its height. Several subtypes of serotonin (5-HT) receptors were proposed on the basis of radioligand binding assays. In order to provide further support to the existence of these receptors we performed quantitative autoradiographic mapping of ...
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Distribution of Serotonin Receptors

Annals of the New York Academy of Sciences, 1990
J M, Palacios   +3 more
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[Are the serotonin receptors life receptors?].

Vestnik Rossiiskoi akademii meditsinskikh nauk, 1995
The paper gives evidence for the fact that serotonin and serotonin receptors are responsible for the occurrence of primary contractions of smooth muscles, primary cardiac contractions and primary brain electric activity (EEG genesis). It is concluded that the function of the smooth muscle, brain and heart cannot take place without serotonin and its ...
A P, Simonenkov   +7 more
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