Anabolic effects of IGF-1 signaling on the skeleton [PDF]
, 2013 This review focuses on the anabolic effects of IGF-1 signaling on the skeleton, emphasizing the requirement for IGF-1 signaling in normal bone formation and remodeling.
Candice G. T. Tahimic +2 more
core +2 more sources
Untersuchung zur IGF-I-vermittelten Signaltransduktion in der humanen Karzinoidzellinie LCC-18 [PDF]
, 2004 In dieser Arbeit wurde die Wachstumsregulation der Zellinie LCC-18 durch IGF-I untersucht. Die Zellinie LCC-18 wurde aus einem humanen Kolon-Karzinoid etabliert und zeigte stabile neuroendokrine Eigenschaften über eine Dauer von über 100 Zellpassagen ...
Göke, Rüdiger (Prof. Dr. med.) +1 more
core +1 more source
牛尾椎椎間板におけるインスリン様成長因子-1(IGF-1)の自己分泌機構及びIGF-1が椎間板のプロテオグリカン合成に与える影響 [PDF]
, 1996 The present study was undertaken to investigate the effect of IGF-1 on proteoglycan (PG) synthesis and the autocrine/paracrine mechanisms involving insulin-like growth factor-1 (IGF-1) in the bovine coccygeal intervertebral disc.IGF-1 stimulated PG ...
Osada Ryusuke
core +1 more source
Expression of hormonal receptors in osteosarcomas of the jaw bones: clinico-pathological analysis of 21 cases [PDF]
, 2013 Background: Sexual hormones have an important role in many hormone-dependant tumors like breast and prostate carcinomas, and also a relationship has been found with bone metabolism and bone tumors.
Cano-Valdez, Ana María +4 more
core +1 more source
Research reports of NKJ hormone symposium : Korpilampi, Finland 4-5 January 1979 [PDF]
, 1999 vKirjasto Aj-
Kossila, Vappu (edited) +1 more
core
New treatment strategies for growth failure caused by chronic inflammation in children [PDF]
, 2013 Chronic inflammation during childhood often leads to impaired bone growth and reduced height in adulthood. Interleukin-1β (IL-1β), interleukin-6 (IL-6) and the tumour necrosis factor-α (TNF-α) are pro-inflammatory cytokines up-regulated during chronic ...
Fernández Vojvodich, Paola
core +1 more source
Journal of Investigative Dermatology, 1986 A membrane receptor for insulin on cultured human keratinocyte monolayers has recently been reported. It has also been established by previous investigators that the receptors for insulin and the somatomedin peptide, insulin-like growth factor-I/somatomedin-C (IGF-I), have similar oligomeric composition.
Brian J. Nickoloff +4 more
openaire +3 more sources
Monitoring serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3), IGF-I/IGFBP-3 molar ratio and leptin during growth hormone treatment for disordered growth [PDF]
, 2000 OBJECTIVE: Serum IGF-I levels are monitored during GH replacement treatment in adults with GH defi- ciency (GHD) to guide GH dose adjustment and to minimize occurrence of GH-related side-effects.
Clayton, P.E. +7 more
core
Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen. [PDF]
, 1988 IL-2 potentiates both growth and cytotoxic function of T lymphocytes and NK cells. Resting peripheral blood NK cells can respond directly to rIL-2, without requirement for accessory cells or cofactors, and enhanced cytotoxicity can be measured within a ...
Barney, C +6 more
core
The IGF1 Signaling Pathway: From Basic Concepts to Therapeutic Opportunities. [PDF]
Int J Mol Sci, 2023 Werner H.
europepmc +1 more source