Receptors, somatomedin - Open Access .click

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Proteoglycan 4 (PRG4) treatment improves skin wound healing in a porcine model

The FASEB Journal, Volume 38, Issue 6, 31 March 2024.
Proteoglycan 4 (PRG4) is commonly found in synovial fluid of the articular joint and serves as a boundary lubricant of articular cartilage. Interestingly, we show that human recombinant proteoglycan 4 (rhPRG4) improves healing of porcine full‐thickness skin injuries. rhPRG4 treatment decreases fibrosis, increases vascularization, and retains adipocytes
Nicoletta Ninkovic +5 more
wiley +1 more source

Advances in the Use of Biologics and Biomaterials toward the Improvement of Pancreatic Islet Graft Survival in Type 1 Diabetes

Advanced NanoBiomed Research, Volume 4, Issue 3, March 2024.
Although islet transplantation has the potential to serve as a curative treatment for type 1 diabetes, there are many hurdles to achieving long‐term islet graft survival. This review discusses the recent advances in strategies to improve islet survival function using exogenous compounds and conformal coatings as a promising tool for improving islet ...
Michael Yilma Yitayew, Marina Luginina, Maryam Tabrizian +2 more
wiley +1 more source

Characterization of Insulin-Like Growth Factor-I/Somatomedin-C Receptors on Human Keratinocyte Monolayers

Journal of Investigative Dermatology, 1986
A membrane receptor for insulin on cultured human keratinocyte monolayers has recently been reported. It has also been established by previous investigators that the receptors for insulin and the somatomedin peptide, insulin-like growth factor-I/somatomedin-C (IGF-I), have similar oligomeric composition.
Misra, Pratima +4 more
openaire +2 more sources

The IGF1 Signaling Pathway: From Basic Concepts to Therapeutic Opportunities. [PDF]