Results 31 to 40 of about 537,907 (152)
Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors. [PDF]
, 2015 GABAA receptors are important for inhibition in the CNS where neurosteroids and protein kinases are potent endogenous modulators. Acting individually, these can either enhance or depress receptor function, dependent upon the type of neurosteroid or ...
Adams, JM +5 more
core +1 more source
Acta Crystallographica Section D, Volume 81, Issue 8, Page 451-464, August 2025.Very high‐resolution fatty acid‐binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially overlooked problem in other, lower resolution, crystal structures of protein–ligand complexes, it has repercussions for any study using such structures ...
Andreas Ehler +4 more
wiley +1 more source
Structural Similarity of Human and Bovine Somatomedin Receptors and Human Insulin Receptor: Analysis by Affinity Labeling [PDF]
Pediatric Research, 1981 The growth promoting and insulin-like actions of somatomedin-C (Sm-C) are thought to be mediated respectively by interactions with the Sm-C and insulin (In) receptors. Since Sm-C and In are structurally homologous, we compared the size and subunit structure of their respective radiolabeled receptors in human placental membranes (hPM) and bovine ...
S Chernausek +3 more
openaire +1 more source
Journal of Experimental Orthopaedics, Volume 12, Issue 2, April 2025.Abstract Purpose The treatment of Achilles tendon (AT) rupture can be conservative or surgical; the latter is better indicated in high‐performance athletes. The pursuit of faster recovery and reductions in skin complications and re‐ruptures have improved the tendon repair technique and early assisted rehabilitation programs.
Rogério de Andrade Gomes +8 more
wiley +1 more source
Aquaculture Research, Volume 2025, Issue 1, 2025.Probiotics and spirulina are used to improve health, growth, and immunity of fish. The purpose of this study was to evaluate the effects of water additive probiotics and dietary Spirulina platensis on growth (weight gain (WG) and specific growth rate (SGR)), hematobiochemical parameters (hemoglobin (Hb) and blood glucose (Glu)), intestinal histology ...
Muallimul Islam +6 more
wiley +1 more source
Distinct pharmacological and functional properties of NMDA receptors in mouse cortical astrocytes [PDF]
, 2011 Background and purpose Astrocytes of the mouse neocortex express functional NMDA receptors which are not blocked by Mg2+ions. However, study of the pharmacological profile of glial NMDARs and their subunit composition is far from complete ...
Lalo, Ulyana +5 more
core +1 more source
Insulin‐Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes
Journal of Diabetes Research, Volume 2025, Issue 1, 2025.The insulin‐like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems. This axis comprises two growth factors, IGF‐I and IGF‐II, and six insulin‐like growth factor–binding proteins (IGFBPs), modulating IGF activity.
Aleksandra Gladych-Macioszek +6 more
wiley +1 more source
Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview
Food Science &Nutrition, Volume 12, Issue 11, Page 8715-8741, November 2024.This comprehensive review explores the sources, structures, physiochemical properties, absorption, metabolism, and functional advantages of lycopene and beta‐carotene, crucial carotenoid antioxidants for human health. We discuss their roles in disease prevention, including cardiovascular disease, cancer, and metabolic disorders, as well as their ...
Tabussam Tufail +5 more
wiley +1 more source
Chondroitin sulfate in invertebrate development
Proteoglycan Research, Volume 2, Issue 4, October-December 2024.Abstract Chondroitin sulfate (CS) is one of the most evolutionarily conserved glycosaminoglycans (GAGs). Although CS's function in skeletal development is well established in vertebrates, CS exists in more primitive animal species with no cartilage or bone, such as C.
Ayano Moriya +3 more
wiley +1 more source
Clinical Case Reports, Volume 12, Issue 9, September 2024.Key Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported. We report on the association of central hypothyroidism and cholesterol with roxadustat.
Serina Kita +9 more
wiley +1 more source