Results 21 to 30 of about 2,004 (138)

2‐Octyl cyanoacrylate adjuvant use in calcaneal tendon repair: A comparative experimental study in rabbits

Journal of Experimental Orthopaedics, Volume 12, Issue 2, April 2025.
Abstract Purpose The treatment of Achilles tendon (AT) rupture can be conservative or surgical; the latter is better indicated in high‐performance athletes. The pursuit of faster recovery and reductions in skin complications and re‐ruptures have improved the tendon repair technique and early assisted rehabilitation programs.
Rogério de Andrade Gomes, Marco Antônio Percope de Andrade, Luiz Eduardo Moreira Teixeira, Bruno Jannotti Pádua, Sidney Max E. Silva, Matheus Maciel Vilela, Paulo Feliciano Sarquis Dias, Eduardo Paulino Júnior, Ivana Duval de Araújo   +8 more
wiley   +1 more source

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C. [PDF]

Proceedings of the National Academy of Sciences, 1983
The effect of phorbol esters on the extent of phosphorylation of receptors for insulin and somatomedin C (insulin-like growth factor I) was studied in intact IM-9 cells that were labeled by incubation with H332PO4. The tumor-promoting phorbol esters phorbol tetradecanoate acetate (TPA) and phorbol dibutyrate, but not the inactive 4 alpha-phorbol ...
S, Jacobs, N E, Sahyoun, A R, Saltiel, P, Cuatrecasas   +3 more
openaire   +2 more sources

Probiotics and Spirulina platensis Improved Growth Performance of Nile Tilapia (Oreochromis niloticus) by Upgrading Intestinal Morphology and Activating GH/IGF Axis

Aquaculture Research, Volume 2025, Issue 1, 2025.
Probiotics and spirulina are used to improve health, growth, and immunity of fish. The purpose of this study was to evaluate the effects of water additive probiotics and dietary Spirulina platensis on growth (weight gain (WG) and specific growth rate (SGR)), hematobiochemical parameters (hemoglobin (Hb) and blood glucose (Glu)), intestinal histology ...
Muallimul Islam, Haphsa Khanom, Naimul Islam, Fouzia Fariha, Bilal Ahamad Paray, Md Mahiuddin Zahangir, Md Shahjahan   +6 more
wiley   +1 more source

Insulin‐Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes

Journal of Diabetes Research, Volume 2025, Issue 1, 2025.
The insulin‐like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems. This axis comprises two growth factors, IGF‐I and IGF‐II, and six insulin‐like growth factor–binding proteins (IGFBPs), modulating IGF activity.
Aleksandra Gladych-Macioszek, Katarzyna Ozegowska, Sandra Radzicka-Mularczyk, Rafał Sibiak, Gernot Desoye, Ewa Wender-Ozegowska, Pawel Stanirowski   +6 more
wiley   +1 more source

Competitive Binding of Somatomedin to the Insulin Receptors of Adipocytes, Chondrocytes, and Liver Membranes [PDF]

Proceedings of the National Academy of Sciences, 1972
The action of growth hormone on skeletal tissue is mediated through somatomedin, a low molecular weight peptide found in serum. This peptide, formerly known as “sulfation factor” or “thymidine factor,” produces marked insulin-like effects in various target tissues. Since at least some of the metabolic effects of insulin on target cells are
R L, Hintz, D R, Clemmons, L E, Underwood, J J, Van Wyk   +3 more
openaire   +2 more sources

Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview

Food Science &Nutrition, Volume 12, Issue 11, Page 8715-8741, November 2024.
This comprehensive review explores the sources, structures, physiochemical properties, absorption, metabolism, and functional advantages of lycopene and beta‐carotene, crucial carotenoid antioxidants for human health. We discuss their roles in disease prevention, including cardiovascular disease, cancer, and metabolic disorders, as well as their ...
Tabussam Tufail, Huma Bader Ul Ain, Sana Noreen, Ali Ikram, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi   +5 more
wiley   +1 more source

Chondroitin sulfate in invertebrate development

Proteoglycan Research, Volume 2, Issue 4, October-December 2024.
Abstract Chondroitin sulfate (CS) is one of the most evolutionarily conserved glycosaminoglycans (GAGs). Although CS's function in skeletal development is well established in vertebrates, CS exists in more primitive animal species with no cartilage or bone, such as C.
Ayano Moriya, Eriko Nakato, Jin‐Ping Li, Hiroshi Nakato   +3 more
wiley   +1 more source

Proteomic exploration of potential blood biomarkers in haemophilic arthropathy

Health Science Reports, Volume 7, Issue 9, September 2024.
Abstract Background and Aims The pathophysiology of haemophilic arthropathy (HA) is complex and largely undefined. Proteomic analyses provide insights into the intricate mechanisms of the HA. Our study aimed to identify differentially expressed proteins in relation to the severity of HA, explore their pathophysiological roles, and evaluate their ...
Nataša Kalebota, Ruđer Novak, Stela Hrkač, Porin Perić, Grgur Salai, Marko Močibob, Marija Pranjić, Zbyněk Zdráhal, Václav Pustka, Nadica Laktašić Žerjavić, Milan Milošević, Marijo Vodanović, Silva Zupančić Šalek, Lovorka Grgurević   +13 more
wiley   +1 more source

Early life interventions metformin and trodusquemine metabolically reprogram the developing mouse liver through transcriptomic alterations

Aging Cell, Volume 23, Issue 9, September 2024.
This study examined the effects of metformin (MF) and trodusquemine (MSI‐1436) on the livers of young, developing mice. We discovered that MSI‐1436 significantly alters mRNA and miRNA expression more potently than MF, impacting key metabolic pathways.
Sarah A. Ashiqueali, Augusto Schneider, Xiang Zhu, Ewelina Juszczyk, Mishfak A. M. Mansoor, Yun Zhu, Yimin Fang, Bianka M. Zanini, Driele N. Garcia, Natalie Hayslip, David Medina, Samuel McFadden, Robert Stockwell, Rong Yuan, Andrzej Bartke, Michael Zasloff, Shadab Siddiqi, Michal M. Masternak   +17 more
wiley   +1 more source

Scale‐Dependent Rheology of Synovial Fluid Lubricating Macromolecules

Small, Volume 20, Issue 21, May 23, 2024.
A multiscale methodology using optical tweezers is developed to examine the interactions between hyaluronic acid (HA) and proteoglycan‐4 (PRG4/lubricin), which are major lubricating biomolecules of synovial fluid in the joints. For the first time, the length scale dependent structure and rheology in solution are characterized, providing a framework for
Leonardo Martin‐Alarcon, Aleksandra Govedarica, Randy H. Ewoldt, Steven L. Bryant, Gregory D. Jay, Tannin A. Schmidt, Milana Trifkovic   +6 more
wiley   +1 more source