Results 21 to 30 of about 2,018 (137)
Journal of Experimental Orthopaedics, Volume 12, Issue 2, April 2025.Abstract Purpose The treatment of Achilles tendon (AT) rupture can be conservative or surgical; the latter is better indicated in high‐performance athletes. The pursuit of faster recovery and reductions in skin complications and re‐ruptures have improved the tendon repair technique and early assisted rehabilitation programs.
Rogério de Andrade Gomes +8 more
wiley +1 more source
Aquaculture Research, Volume 2025, Issue 1, 2025.Probiotics and spirulina are used to improve health, growth, and immunity of fish. The purpose of this study was to evaluate the effects of water additive probiotics and dietary Spirulina platensis on growth (weight gain (WG) and specific growth rate (SGR)), hematobiochemical parameters (hemoglobin (Hb) and blood glucose (Glu)), intestinal histology ...
Muallimul Islam +6 more
wiley +1 more source
Insulin‐Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes
Journal of Diabetes Research, Volume 2025, Issue 1, 2025.The insulin‐like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems. This axis comprises two growth factors, IGF‐I and IGF‐II, and six insulin‐like growth factor–binding proteins (IGFBPs), modulating IGF activity.
Aleksandra Gladych-Macioszek +6 more
wiley +1 more source
Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview
Food Science &Nutrition, Volume 12, Issue 11, Page 8715-8741, November 2024.This comprehensive review explores the sources, structures, physiochemical properties, absorption, metabolism, and functional advantages of lycopene and beta‐carotene, crucial carotenoid antioxidants for human health. We discuss their roles in disease prevention, including cardiovascular disease, cancer, and metabolic disorders, as well as their ...
Tabussam Tufail +5 more
wiley +1 more source
Chondroitin sulfate in invertebrate development
Proteoglycan Research, Volume 2, Issue 4, October-December 2024.Abstract Chondroitin sulfate (CS) is one of the most evolutionarily conserved glycosaminoglycans (GAGs). Although CS's function in skeletal development is well established in vertebrates, CS exists in more primitive animal species with no cartilage or bone, such as C.
Ayano Moriya +3 more
wiley +1 more source
Clinical Case Reports, Volume 12, Issue 9, September 2024.Key Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported. We report on the association of central hypothyroidism and cholesterol with roxadustat.
Serina Kita +9 more
wiley +1 more source
Proteomic exploration of potential blood biomarkers in haemophilic arthropathy
Health Science Reports, Volume 7, Issue 9, September 2024.Abstract Background and Aims The pathophysiology of haemophilic arthropathy (HA) is complex and largely undefined. Proteomic analyses provide insights into the intricate mechanisms of the HA. Our study aimed to identify differentially expressed proteins in relation to the severity of HA, explore their pathophysiological roles, and evaluate their ...
Nataša Kalebota +13 more
wiley +1 more source
Aging Cell, Volume 23, Issue 9, September 2024.This study examined the effects of metformin (MF) and trodusquemine (MSI‐1436) on the livers of young, developing mice. We discovered that MSI‐1436 significantly alters mRNA and miRNA expression more potently than MF, impacting key metabolic pathways.
Sarah A. Ashiqueali +17 more
wiley +1 more source
Scale‐Dependent Rheology of Synovial Fluid Lubricating Macromolecules
Small, Volume 20, Issue 21, May 23, 2024.A multiscale methodology using optical tweezers is developed to examine the interactions between hyaluronic acid (HA) and proteoglycan‐4 (PRG4/lubricin), which are major lubricating biomolecules of synovial fluid in the joints. For the first time, the length scale dependent structure and rheology in solution are characterized, providing a framework for
Leonardo Martin‐Alarcon +6 more
wiley +1 more source
Proteoglycan 4 (PRG4) treatment improves skin wound healing in a porcine model
The FASEB Journal, Volume 38, Issue 6, 31 March 2024.Proteoglycan 4 (PRG4) is commonly found in synovial fluid of the articular joint and serves as a boundary lubricant of articular cartilage. Interestingly, we show that human recombinant proteoglycan 4 (rhPRG4) improves healing of porcine full‐thickness skin injuries. rhPRG4 treatment decreases fibrosis, increases vascularization, and retains adipocytes
Nicoletta Ninkovic +5 more
wiley +1 more source