Results 1 to 10 of about 2,004 (138)

Differences in the Expression of Insulin-Like Growth Factor Signaling Pathway Members in Patients With Psoriasis Vulgaris and Controls. [PDF]

Mediators Inflamm
Insulin‐like growth factors (IGFs) and IGF–binding proteins (IGFBPs) regulate cell proliferation, differentiation, metabolic processes, and immune activities. Psoriasis is a systemic inflammatory disease with metabolic disorders as an important comorbidity in the pathogenesis of which members of the IGF family could also play a role.
Drahomira H, Lenka B, Zdenek F, Jan K, Kvetoslava H, Eva C, Vit R, Ondrej F, Tereza M, Pavel B.   +9 more
europepmc   +2 more sources

Correlation between sleep problems and morning serum melatonin and ferritin levels in Japanese 5-year-old children with autism spectrum disorder. [PDF]

PCN Rep
Abstract Aim Children with autism spectrum disorder (ASD) are more likely to have sleep problems. Few studies have investigated the relationship between sleep problems and blood melatonin and ferritin levels. The objective of this study was to determine the correlation between sleep problems and morning serum melatonin and ferritin levels, and the ...
Terui A, Saito M, Kuki A, Shimoyama S, Sakamoto Y, Yoshida K, Osato A, Nakamura K.   +7 more
europepmc   +2 more sources

Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat. [PDF]

Clin Case Rep
Key Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported. We report on the association of central hypothyroidism and cholesterol with roxadustat.
Kita S, Okuyama H, Kondo T, Hayashi M, Nakao S, Sawamura T, Fujimoto K, Nakagawa A, Yokoyama H, Furuichi K.   +9 more
europepmc   +2 more sources

Association of Acromegaly and Multiple Myeloma: A Case Report

Endocrinology Research and Practice, 2013
Malignancy is an important cause of mortality in acromegaly. Hematological malignancies are very rare in acromegaly. Here, we report an 80-year-old patient with acromegaly and multiple myeloma. Patient died within a month of diagnosis.
Murat Atmaca, Saliha Yıldız, Işılay Kalan, Mehmet Fatih Özbay, İsmet Seven, Mustafa Öztürk   +5 more
doaj   +1 more source

Relationship of Insulin-like Growth Factor Receptor Single Nucleotide 
Polymorphism (SNP) with Platinum-based Chemotherapy Outcomes in Advanced Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2012
Background and objective It has been proven that the insulin-like growth factor 1 receptor (IGF-1R) gene is an important regulator of many aspects of growth, differentiation, and development.
Yusheng CHEN, Hui SHAO, Hongru LI, Lili HAN, Xiang'e ZHANG   +4 more
doaj   +1 more source

Monensin blocks the maturation of receptors for insulin and somatomedin C: Identification of receptor precursors [PDF]

Proceedings of the National Academy of Sciences, 1983
Cultured human lymphoid (IM-9) cells were labeled with [ 35 S]methionine in the presence and absence of monensin, a carboxylic ionophore that inhibits post-translational protein maturation. Labeled receptors for insulin and somatomedin C were immunoprecipitated with antibodies specific for each receptor.
S, Jacobs, F C, Kull, P, Cuatrecasas
openaire   +2 more sources

Ontogenesis of somatomedin and insulin receptors in the human fetus. [PDF]

Journal of Clinical Investigation, 1983
This study examines the ontogenesis of somatomedin and insulin receptors in man. Particulate plasma membranes were prepared by ultracentrifugation from various tissues removed from fetuses after abortion and classified as less than 17, 17-25, and greater than 25 cm in length.
V R, Sara, K, Hall, M, Misaki, L, Fryklund, N, Christensen, L, Wetterberg   +5 more
openaire   +2 more sources

Stimulation of glycosaminoglycan synthesis by somatomedin and insulin in rat chondrocytes via somatomedin receptors.

Endocrinologia Japonica, 1984
Using cultured normal rat chondrocytes we have investigated 1) the effects of somatomedin and insulin on glycosaminoglycan (GAG) synthesis and 2) somatomedin and insulin binding sites. We confirmed that somatomedin and insulin stimulate GAG synthesis in normal rat chondrocytes.
K, Asakawa, K, Takano, N, Hizuka, M, Kogawa, K, Shizume   +4 more
openaire   +3 more sources

The relationship between the concentration of insulin-like growth factor, leptin and lipid metabolism indices in the blood of dairy cows during different physiological periods

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
Despite the evidence of the fundamental influence of the endocrine system on metabolism in ruminants, there is little literature on hormonal status. There is insufficient data on tissue hormones, particularly insulin-like growth factor and leptin.
M. R. Simonov, V. V. Vlizlo, T. О. Pundiak, B. V. Gutyj, L. G. Slivinska, I. I. Kovalchuk   +5 more
doaj   +1 more source

Somatomedin receptor of human placenta: solubilization, photolabeling, partial purification, and comparison with insulin receptor. [PDF]

Proceedings of the National Academy of Sciences, 1981
Using a recently isolated human basic somatomedin (basic SM) similar to insulin-like growth factor I (IGF-I), we studied both the photoaffinity-labeled and unlabeled basic-SM receptor solubilized from human placental cell membranes. Unlike the result with the insulin receptor, high yields of soluble basic-SM-binding activity are obtained with Triton X ...
B, Bhaumick, R M, Bala, M D, Hollenberg
openaire   +2 more sources