Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor. [PDF]
Phosphorylation of the somatomedin-C receptor was investigated both in intact IM-9 cells and in IM-9 cells that had been solubilized with Triton X-100. Intact IM-9 cells were incubated with [32P]H3PO4 for 1 h and for an additional 5 min in the absence or presence of insulin or somatomedin-C.
S, Jacobs +5 more
openaire +3 more sources
Differences in the Expression of Insulin-Like Growth Factor Signaling Pathway Members in Patients With Psoriasis Vulgaris and Controls. [PDF]
Insulin‐like growth factors (IGFs) and IGF–binding proteins (IGFBPs) regulate cell proliferation, differentiation, metabolic processes, and immune activities. Psoriasis is a systemic inflammatory disease with metabolic disorders as an important comorbidity in the pathogenesis of which members of the IGF family could also play a role.
Drahomira H +9 more
europepmc +2 more sources
Regulation of human fibroblast insulin-like growth factor (IGF)-binding proteins by IGF-1 and cytokines, mechanisms of action and effects upon IGF bioactivity [PDF]
PhDThe insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth and development.
Yateman, Martin Edward
core +4 more sources
Characterisation of bovine leukocyte Ig-like receptors [PDF]
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC +8 more
core +4 more sources
Somatomedin C in dairy cows related to energy and protein supply and to milk production [PDF]
Somatomedin C and other hormones, as well as blood metabolites, were measured during the dry period and during lactation in dairy cows, given different amounts of energy and protein, to study metabolic and endocrine adaptations.
Jans, F +17 more
core +2 more sources
Correlation between sleep problems and morning serum melatonin and ferritin levels in Japanese 5-year-old children with autism spectrum disorder. [PDF]
Abstract Aim Children with autism spectrum disorder (ASD) are more likely to have sleep problems. Few studies have investigated the relationship between sleep problems and blood melatonin and ferritin levels. The objective of this study was to determine the correlation between sleep problems and morning serum melatonin and ferritin levels, and the ...
Terui A +7 more
europepmc +2 more sources
Insulin-Like Growth Factor (IGF)-I and -11 and IGFBinding Proteins-l, -2, and -3 in Children and Adolescents with Diabetes Mellitus: Correlation with Metabolic Control and Height Attainment. [PDF]
The putative effects of diabetes and metabolic control on circulating levels of insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) remain controversial.
Past, Roswitha +6 more
core +1 more source
Characterization of Insulin-Like Growth Factor-I/Somatomedin-C Receptors on Human Keratinocyte Monolayers [PDF]
A membrane receptor for insulin on cultured human keratinocyte monolayers has recently been reported. It has also been established by previous investigators that the receptors for insulin and the somatomedin peptide, insulin-like growth factor-I ...
Misra, Pratima +4 more
core +1 more source
Hormonal Control of Immunoreactive Somatomedin Production by Cultured Human Fibroblasts [PDF]
Human growth hormone (hGH) is known to be a potent stimulator of somatomedin secretion in vivo. The induction of somatomedin by growth hormone has been difficult to study in vitro, however, because no organ containing a high concentration of somatomedin ...
Underwood, Louis E. +5 more
core +1 more source
Sequential addition of platelet factor and plasma to balb/c3t3 fibroblast cultures stimulates somatomedin-c binding early in cell cycle. [PDF]
Recent studies have shown that confluent cultured fibroblasts must be rendered competent by a factor contained in platelets before they can respond to plasma components and progress from G0 to S phase of the cell cycle.
Pledger, W. J. +5 more
core +1 more source

