Results 161 to 170 of about 2,382,295 (256)

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu, Jing‐Wen Hou, Zhong‐Ying Lv, Ming‐Hui Sun, Xiao‐Yang Zhang, Lei Zhang, Mei Wang   +6 more
wiley   +1 more source

Targeting the apical domain of the transferrin receptor: Development of a new protein scaffold for cellular delivery. [PDF]

Protein Sci
Veetil AA, Sjöström DJ, Iribarren C, Mohlin C, Ambrosetti E, Bjelic S.   +5 more
europepmc   +1 more source

Enrichment of Hyaluronic Acid Binding Tumor Cells by Modulation of Selective Adhesion on Microgel Surfaces

Macromolecular Rapid Communications, EarlyView.
We have developed a thermoresponsive microgel system for the selective enrichment of hyaluronic acid‐binding tumor cells. By modulating the adhesion on the microgel surface via temperature changes from 37°C to 30°C, we demonstrate a novel proof‐of‐principle for separating these tumor cell from white blood cells, which has potential applications in ...
Melanie Schmidt, Dilay Karayel, André Franken, Janita Müller, Laura Hartmann, Klaus Pantel, Tanja Fehm, Hans Neubauer, Stephan Schmidt   +8 more
wiley   +1 more source

Transferrin receptors in rat plasma.

Proceedings of the National Academy of Sciences of the United States of America, 1988
Yves Beguin, H. Huebers, B. Josephson, Clement A. Finch   +3 more
semanticscholar   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Exosome engineering for targeted therapy of brain-infecting pathogens: molecular tools, delivery platforms, and translational advances. [PDF]

Front Med Technol
Onohuean H, Naik Bukke SP, Thalluri C, Abass KS, Choonara YE.   +4 more
europepmc   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

Serum soluble transferrin receptor (sTfR) in HFpEF: associations with cardiac function and exercise tolerance. [PDF]

Eur J Med Res
Ma J, Zhao J, Jia G.
europepmc   +1 more source

Role of transferrin, Fe, and transferrin receptors in myeloid leukemia cell growth. Studies with an antitransferrin receptor monoclonal antibody.

Journal of Clinical Investigation, 1985
R. Taetle, K. Rhyner, J. Castagnola, D. To, J. Mendelsohn   +4 more
semanticscholar   +1 more source

Barriers to timely nutrition support in patients with cancer: A scoping review

Nutrition in Clinical Practice, EarlyView.
Abstract In clinical cancer settings, malnutrition can go undiagnosed and patients often receive nutrition care only after they have lost substantial weight or developed severe side effects. Neglecting to provide nutrition care to a patient in a timely manner can lead to increased difficulties in supporting them and to poorer clinical outcomes. The aim
Francesca Tabacchi, Thomas Mitaras, Vasiliki Iatridi, Jonathan Tammam, Eila Watson, Shelly Coe   +5 more
wiley   +1 more source