Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
Frontiers in Pharmacology, 2020 Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface.
Mengji Chen +4 more
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Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke. [PDF]
PLoS ONE, 2011 We identified that the angiotensin receptor antagonist, candesartan, has profound neurovascular protective properties when administered after ischemic stroke and was associated with a proangiogenic state at least partly explained by vascular endothelial ...
Weihua Guan +9 more
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Exercise Training Ameliorates The Tramadol-Induced Toxicity on VEGF/VEGFRs/PI3K/AKT Signaling Pathway in Testicular Tissue after Tramadol Withdrawal [PDF]
International Journal of Fertility and SterilityBackground: The study investigated how exercise training protocols (ETPs) with different intensities can amelioratethe tramadol (TRA)-induced toxicity in the testicular tissue by upregulating VEGF/VEGFRs/PI3K/AKT signalingpathway in the post-withdrawal ...
Vahid Saeidifard +3 more
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Frontiers in Bioscience-Landmark, 2023 Background: In addition to intrahepatic angiogenesis, patients with cholestasis cirrhosis develop extrahepatic vasculature disorders and functional disturbances of multiple organ systems.
Dandan Wang +14 more
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Signal Transduction by Vascular Endothelial Growth Factor Receptors [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 Vascular endothelial growth factors (VEGFs) are master regulators of vascular development and of blood and lymphatic vessel function during health and disease in the adult. It is therefore important to understand the mechanism of action of this family of five mammalian ligands, which act through three receptor tyrosine kinases (RTKs).
Sina, Koch, Lena, Claesson-Welsh
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Structural and functional characterization of the intracellular kinase domain of vascular endothelial growth factor receptor-2 [PDF]
, 2013 Vascular Endothelial Growth Factors (VEGFs) are key players in blood and lymphatic vessel development and homeostasis. The family consists of five members, VEGF-A, -B, -C, -D and placenta growth factor (PLGF).
Manni, Sandro
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Frontiers in Oncology, 2023 Nintedanib is a tyrosine kinase inhibitor of fibroblast growth factor-, vascular endothelial growth factor-, and platelet-derived growth factor receptors.
Shu Yan +6 more
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Brain homeostasis : VEGF receptor 1 and 2 ; two unequal brothers in mind [PDF]
, 2013 Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the vascular system, exert trophic effects on neural cells during development and adulthood.
Karl H. Plate +5 more
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Vascular Endothelial Growth Factor Increases Urokinase Receptor Expression in Vascular Endothelial Cells [PDF]
Journal of Biological Chemistry, 1995 Vascular endothelial growth factor (VEGF) is a potent angiogenic factor and endothelial cell-specific mitogen that stimulates urokinase-type plasminogen activator (uPA) activity in vascular endothelial cells. Here, we report that VEGF increases the high affinity binding of uPA to the same cells and that this binding is prevented by a peptide ...
Mandriota, Stephano J. +7 more
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CD8 T-cell induction against vascular endothelial growth factor receptor 2 by Salmonella for vaccination purposes against a murine melanoma. [PDF]
, 2012 The Salmonella type III secretion system (T3SS) efficiently translocates heterologous proteins into the cytosol of eukaryotic cells. This leads to an antigen-specific CD8 T-cell induction in mice orally immunized with recombinant Salmonella. Recently, we
Jellbauer, Stefan +7 more
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