Results 1 to 10 of about 8,058 (56)

A Natural Variant Type II G Protein-coupled Receptor for Vasoactive Intestinal Peptide with Altered Function [PDF]

Journal of Biological Chemistry, 2004
The vasoactive intestinal peptide (VIP) and its G protein-coupled receptors VPAC1 and VPAC2 prominently mediate diverse physiological functions in the neural, endocrine, and immune systems. A deletion variant of mouse VPAC2 has been identified in immune cells that lacks amino acids 367-380 at the carboxyl-terminal end of the seventh transmembrane ...
Carola, Grinninger, Wengang, Wang, Kaveh Bastani, Oskoui, Julia K, Voice, Edward J, Goetzl   +4 more
openaire   +2 more sources

Functional Splice Variants of the Type II G Protein–Coupled Receptor (VPAC2) for Vasoactive Intestinal Peptide in Mouse and Human Lymphocytes [PDF]

Annals of the New York Academy of Sciences, 2006
Abstract:  A PCR‐based search for splice variants of the VPAC2 G protein–coupled receptor for vasoactive intestinal peptide (VIP) revealed: (a) a short‐deletion variant in mouse lymphocytes termed VPAC2de367–380, that lacks 14 amino acids in the seventh transmembrane domain, and (b) a long‐deletion variant in human lymphocytes termed VPAC2de325–438 ...
Allison L, Miller, Deepti, Verma, Carola, Grinninger, Mei-Chuan, Huang, Edward J, Goetzl   +4 more
openaire   +2 more sources

Roles of Vasoactive Intestinal Peptide (VIP) in the Expression of Different Immune Phenotypes by Wild-Type Mice and T Cell-Targeted Type II VIP Receptor Transgenic Mice [PDF]

The Journal of Immunology, 2003
Abstract Vasoactive intestinal peptide (VIP) and its two G protein-coupled receptors, VPAC1 and VPAC2, are quantitatively prominent and functionally critical in the immune system. Transgenic (T) mice constitutively expressing VPAC2 selectively in CD4 T cells, at levels higher than those found after maximal induction in CD4 T cells of ...
Julia K, Voice, Carola, Grinninger, Yvonne, Kong, Yogesh, Bangale, Sudhir, Paul, Edward J, Goetzl   +5 more
openaire   +2 more sources

Optimized Peptide–MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells

Frontiers in Immunology, 2018
Peptide–MHC (pMHC) multimers have become the “gold standard” for the detection and isolation of antigen-specific T-cells but recent evidence shows that normal use of these reagents can miss fully functional T-cells that bear T-cell receptors (TCRs) with ...
Garry Dolton, Efthalia Zervoudi, Cristina Rius, Aaron Wall, Hannah L. Thomas, Anna Fuller, Lorraine Yeo, Lorraine Yeo, Mateusz Legut, Sophie Wheeler, Meriem Attaf, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Ernest Choy, Ernest Choy, Mark Peakman, Mark Peakman, Andrew K. Sewell, Andrew K. Sewell   +19 more
doaj   +1 more source

Distinguishing Features of ILC2s During Type 2 Immune Responses. [PDF]

Eur J Immunol
Jakob MO, Forster PM, Klose CSN.
europepmc   +1 more source

Neuroplasticity and neuroimmune interactions with type 2 inflammation in asthma. [PDF]

Eur Respir Rev
Koster CS, Lavitola C, Teodorescu R, Bakker BA, Gosens R.   +4 more
europepmc   +1 more source

Aviptadil in Acute Respiratory Distress Syndrome-Promise or Mirage? [PDF]

Indian J Crit Care Med
Chanchalani G.
europepmc   +1 more source

Integrated Genetic and Protein Mechanisms Underlying Glucagon-like Peptide-1 Receptor Agonists in Treating Diabetes Mellitus and Weight Loss. [PDF]

Curr Issues Mol Biol
Francis L, Butler MG.
europepmc   +1 more source

Neuroimmune Crosstalk in Psoriasis: Mechanisms and Therapeutic Implications. [PDF]

Inflammation
Gao H, Fang Y, Zhang Y, Xie T, Chen Z, Wang G.   +5 more
europepmc   +1 more source

Enteric nervous system in microbiota-associated gut inflammation. [PDF]

Front Immunol
Yang C, Lan X, Zhong H, Geng J, Wang W.
europepmc   +1 more source