Results 51 to 60 of about 20,333 (158)
The effects of isatin (indole-2, 3-dione) on pituitary adenylate cyclase-activating polypeptide-induced hyperthermia in rats [PDF]
, 2002 Background Previous studies have demonstrated that centrally administered natriuretic peptides and pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) have hyperthermic properties.
Tóth Gábor +4 more
core +1 more source
Amacrine cell inputs to OFF midget ganglion cells in macaque retina
The Journal of Physiology, EarlyView.Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak +8 more
wiley +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
Studies on inhibitory modulation of urinary tract motility [PDF]
, 2014 Overactive Bladder (OAB) is a symptom syndrome characterized by urgency and frequency, with or without urge incontinence. Research concerning the mechanisms underlying OAB and finding new inhibitory factor(s) is intensive.
Guan, Na
core +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Pellagra may complicate functioning pulmonary atypical carcinoid and present as a subtle acral dermatosis rather than the classical photo‐distributed rash. In neuroendocrine tumor patients with chronic diarrhea and new skin changes, clinicians should suspect niacin deficiency and consider empiric nicotinamide, even when niacin assays are ...
Ahmar Iftikhar Talib +2 more
wiley +1 more source
Receptor oligomerization: from early evidence to current understanding in class B GPCRs [PDF]
, 2013 Dimerization or oligomerization of G protein-coupled receptors (GPCRs) are known to modulate receptor functions in terms of ontogeny, ligand-oriented regulation, pharmacological diversity, signal transduction, and internalization.
Chow, BKC, Lee, TO, Ng, SYL
core +1 more source
Comprehensive Physiology, Volume 16, Issue 2, April 2026.Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu +11 more
wiley +1 more source
Actin cytoskeleton-dependent regulation of corticotropin-releasing factor receptor heteromers [PDF]
, 2017 Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein–coupled receptors, are pivotal in mediating ...
Bhargava, Aditi +7 more
core +1 more source
Genes, Brain and Behavior, Volume 25, Issue 2, April 2026.In the habituation task, locomotion speed, whisker angular position and whisker spread decreased between the first two consecutive sessions in all mice, suggesting that the animals were less focused on sampling the area as they got more familiar with the environment.
Ugne Simanaviciute +5 more
wiley +1 more source
Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell‐Based Therapies
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Graphical presentation of stem cell‐based therapies for arterial dysfunction, endothelial repair and regeneration strategies. SMC, smooth muscle cell. ABSTRACT Arterial regeneration represents a critical frontier in cardiovascular medicine, as progressive endothelial dysfunction, maladaptive vascular smooth muscle cell (SMC) plasticity, and chronic ...
Yun‐Yu Ma, Shu‐Yao Zhu, Yi Song
wiley +1 more source