Results 61 to 70 of about 20,333 (158)
Principles of pharmacological correction of pulmonary arterial hypertension [PDF]
, 2018 Prostanoids are a promising group of drugs for the treatment of pulmonary arterial hypertension (PAH), since they possess not only vasodilating, but also antiplatelet and antiproliferative actions.
Korokin, M. V. +3 more
core +2 more sources
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
Advanced Science, Volume 13, Issue 14, 9 March 2026.This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
The Interplay between Hormones and Irritable Bowel Disease [PDF]
, 2013 Thesis (M.A.)--Boston UniversityThis thesis examines the underlying mechanisms causing the severe and often debilitating symptoms associated with both Irritable Bowel Syndrome and Inflammatory Bowel Disease.
Linson, Elyse A.
core +1 more source
Thyroxine-binding globulin: investigation of microheterogeneity [PDF]
, 1981 Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland +4 more
core +1 more source
Advanced Science, Volume 13, Issue 16, 18 March 2026.This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
wiley +1 more source
Pituitary Adenylate Cyclase-Activating Polypeptide Ameliorates Experimental Acute Ileitis and Extra-Intestinal Sequelae [PDF]
, 1970 Background The neuropeptide Pituitary adenylate cyclase-activating polypeptide (PACAP) plays pivotal roles in immunity and inflammation. So far, potential immune-modulatory properties of PACAP have not been investigated in experimental ileitis ...
Heimesaat, Markus M. +12 more
core +1 more source
Sex and life experience shape locus coeruleus pretangle tau pathology
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Alzheimer's disease features early a pathology in the locus coeruleus (LC), yet how sex and life experience shape LC vulnerability remains poorly understood. METHODS We expressed pseudophosphorylated human tau (htauE14) in LC neurons of TH‐Cre rats and exposed both sexes to early‐ or late‐life enrichment or stress.
Zia Hasan +10 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 2, March 2026.GVO relieves constipation mechanisms. GVO decreased the abundance of Firmicutes and increased that of Bacteroidota, thereby ameliorating Lop‐induced gut microbial imbalances. Then the level of 8,9‐DiHETrE was raised, whereas the level of 15(S)‐HpETE was lowered.
Yanan Xu +11 more
wiley +1 more source
Somatostatin Analogues in the Treatment of Neuroendocrine Tumors: Past, Present and Future [PDF]
, 2019 In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased. Due to the slow-growing nature of these tumors and the lack of early symptoms, most cases are diagnosed at advanced stages, when curative treatment options are no ...
Amthauer, Holger +8 more
core +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Garlic polysaccharides (GP) demonstrated potential against functional constipation. In vitro, GP exhibited digestive resistance properties and boosted beneficial Bifidobacterium and Lactobacillus. In constipated mice, GP alleviated constipation by reducing oxidative stress and repairing the mechanical, chemical, and immune barriers.
Jingfang Li +6 more
wiley +1 more source