Results 211 to 220 of about 50,162 (238)
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Trends in Endocrinology & Metabolism, 2000
The biological effects of arginine vasopressin (AVP) are mediated by three receptor subtypes: the V1a and V1b receptors that activate phospholipases via Gq/11, and the V2 receptor that activates adenylyl cyclase by interacting with Gs. Isolation of the cDNAs encoding the V1a and V1b receptor subtypes explained the tissue variability of V1 antagonist ...
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The biological effects of arginine vasopressin (AVP) are mediated by three receptor subtypes: the V1a and V1b receptors that activate phospholipases via Gq/11, and the V2 receptor that activates adenylyl cyclase by interacting with Gs. Isolation of the cDNAs encoding the V1a and V1b receptor subtypes explained the tissue variability of V1 antagonist ...
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Vasopressin and Vasopressin Receptor Antagonists in Heart Failure
Cardiology in Review, 2009Antidiuretic hormone, also known as arginine vasopressin, is a hormone with a multitude of physiologic activities including the control of urinary free water excretion. Antidiuretic hormone also plays a role in vasoconstriction and has 3 receptors that have been identified.
Marc Klapholz, Gerard Oghlakian
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Palmitoylation of the V2 Vasopressin Receptor
Molecular Pharmacology, 1997Palmitoylation of the V2 vasopressin receptor (V2R) and its functional role were investigated in transfected cells. Palmitoylation was assessed by incubating transfected cells with [3H]palmitic acid and immunoprecipitating the receptor with an antibody raised against a portion of the third intracellular loop of V2R.
H. M. Sadeghi +3 more
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Genetics of vasopressin receptors
Current Hypertension Reports, 2004Membrane receptors that couple to guanine nucleotide binding protein (GPCRs) represent one of the largest families of proteins in the genome. Because of their universal distribution and multiple actions, genetic variations of GPCRs are associated with various human diseases.
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Vascular vasopressin receptors
General Pharmacology: The Vascular System, 19881. Vascular vasopressin receptors are understood because of the specific application of each major technical advance in pharmacology; this review shows that isolated organs, whole animal preparations, hormone synthesis, radioligand binding, and human studies have all played their part. 2. Even so, neither vascular vasopressin receptor heterogeneity nor
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Human platelet vasopressin receptors
Life Sciences, 1982Specific saturable binding of 125I-arginine-vasopressin to human platelets is described. For ten normal volunteers the mean (+/- S.D.) KD is 5.6 nM (+/- 2.1) and the mean (+/- S.D.) Bmax is 115 fmoles/mg protein (+/- 30). Association studies indicate that equilibrium is reached after 90 minutes on ice.
Robert M. Post +3 more
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Vasopressin Receptor Antagonists
Current Hypertension Reports, 2015Arginine vasopressin (AVP) is the principal hormone involved in regulating the tonicity of body fluids. Less appreciated is the role that AVP plays in a variety of other physiologic functions including glucose metabolism, cardiovascular homeostasis, bone metabolism, and cognitive behavior.
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Vasopressin and oxytocin receptors
Baillière's Clinical Endocrinology and Metabolism, 1996The oxytocin and the vasopressin V1a, V1b and V2 receptors have recently been cloned and shown to form a sub-family within the large superfamily of G-protein-linked receptors. Renal V2 receptors mediate vasopressin-induced water reabsorption via induction of intracellular cAMP production in collecting duct cells.
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V2 vasopressin receptor mutations
2020V2 vasopressin receptor (V2R) is a member of the G protein-coupled receptor (GPCR) family in which many disease-causing mutations have been identified and thus generated much interest. Loss-of-function V2R mutations cause nephrogenic diabetes insipidus (NDI) whereas gain-of-function mutations cause nephrogenic syndrome of inappropriate antidiuresis ...
Taroh Iiri +4 more
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Solubilization of Vasopressin Receptors
1991Publisher Summary This chapter provides an overview of the solubilization of vasopressin receptors. Vasopressin is a neurohypophyseal hormone that includes antidiuresis, promotes glycogenolysis in the liver, and contracts vascular smooth muscle, thereby, raising blood pressure.
Ponnal Nambi +2 more
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