Results 191 to 200 of about 51,699 (307)

Enhanced Bioactivity of Puerariae Radix‐ Hovenia Seed Extracts Through Lactiplantibacillus plantarum and Lacticaseibacillus paracasei Co‐Fermentation: Impact on Alcoholic Liver Injury and Macrophage Polarization

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Puerariae Radix and Hovenia Seed were co‐fermented with Lactiplantibacillus plantarum and Lacticaseibacillus paracasei to produce PHF. In a mouse model of alcohol‐induced liver injury, PHF intervention alleviated liver damage. The underlying mechanism may be related to the regulation of macrophage polarization.
Yunpeng Sun   +7 more
wiley   +1 more source

Ultra‐Micro Powder From Edible Plants (Pueraria lobata, Cornus officinalis, Cistanche deserticola, and Dendrobium officinale) Reshapes Intestinal Flora and Attenuates Liver Injury in Alcohol‐Induced Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Ultra‐micro powder from edible plants (Pueraria lobata, Cornus officinalis, Cistanche deserticola, and Dendrobium officinale) attenuates alcoholic liver injury by regulating the gut‐liver axis. It primarily reshapes the intestinal microbiota by restoring beneficial Lactobacillus populations and suppressing pathogenic bacteria like Proteobacteria and ...
Jia‐Yu Huang   +5 more
wiley   +1 more source

A Triterpenoid‐Enriched GLE70 Fraction From Ganoderma lingzhi Ameliorates Alcoholic Liver Disease via Multi‐Target Regulation

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
GLE fractions were prepared from Ganoderma lingzhi using gradient ethanol elution and evaluated for their biological activities. Among the fractions, GLE70 exhibited the strongest antioxidant and hepatoprotective effects. Integrated chemical characterization, network pharmacology, molecular docking, and in vivo validation suggested that GLE70 may exert
Yanjun Chen   +7 more
wiley   +1 more source

Sex-specific single transcript level atlas of vasopressin and its receptor (AVPR1a) in the mouse brain. [PDF]

open access: yesElife
Gumerova AA   +18 more
europepmc   +1 more source

Ergothioneine Ameliorates Alcoholic Fatty Liver Disease: A Dual Strategy of Accelerated Ethanol Elimination and Reducing Oxidative Stress

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.
Ergothioneine (EGT) ameliorates alcoholic fatty liver disease via a dual mechanism: accelerating ethanol clearance by protecting ADH/ALDH activity (serum EtOH decreased 54.4%), and reducing oxidative stress/inflammation via antioxidant restoration (GSH‐Px increased 198.2%) and NF‐κB suppression (IL‐1β decreased 67.1%), collectively reversing hepatic ...
Wei Ding   +5 more
wiley   +1 more source

Defining Acquired Hypothalamic Obesity: An Expert Call for Unified Diagnosis and Therapeutic Action

open access: yes
Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4437-4441, June 2026.
Hanneke M. van Santen   +7 more
wiley   +1 more source

Targeting Tumor Stroma: Current Challenges and Future Directions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang   +7 more
wiley   +1 more source

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