Vasopressor‐Associated Limb Ischemia Resulting in Quadruple Amputation in Suspected Septic Shock
ABSTRACT Vasopressor‐associated limb ischemia (VALI) is a rare but devastating complication of vasopressor therapy in septic shock. This case shows catastrophic four‐limb amputation in a 26‐year‐old obese male with suspected septic shock. This case illustrates the complex interplay between prolonged high‐dose vasopressor therapy, morbid obesity, and ...
Muni Rubens +8 more
wiley +1 more source
Untangling Mephedrone-Induced Social Reward in Rats-The Involvement of Oxytocin and Vasopressin V<sub>1A</sub> Receptors. [PDF]
Wronikowska-Denysiuk O +5 more
europepmc +1 more source
ABSTRACT Acute liver failure with intracranial hemorrhage poses difficult transplant decisions. We report acetaminophen‐induced acute liver failure with cerebral edema and active multifocal hemorrhage successfully managed with emergent liver transplantation and staged neurosurgical intervention.
Daryna Shnitser +3 more
wiley +1 more source
Pharmacologic Strategies for Intraoperative Hypotension When Ephedrine Is Unavailable: An Evidence-Based Review. [PDF]
Duarte-Medrano G +5 more
europepmc +1 more source
Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang +7 more
wiley +1 more source
Case Report: a family presenting with β-adrenergic/vasopressin-responsive bilateral macronodular adrenal disease with an <i>ARMC5</i> mutation treated with metyrapone monotherapy for more than 5 years. [PDF]
Arai M +10 more
europepmc +1 more source
Using rabies‐based monosynaptic retrograde tracing and AAV anterograde labeling, this study maps the brain‐wide inputs and outputs of PVN CRH neurons, identifying them as a key hub coordinating stress, autonomic, and behavioral responses. ABSTRACT Objective The paraventricular nucleus of the hypothalamus (PVN) is a central hub integrating ...
Ziteng Yue +11 more
wiley +1 more source
Nephrogenic Syndrome of Inappropriate Antidiuresis: Case Report and Genetic Perspectives. [PDF]
Chen XJ, Kou M, Feng M, Wang LH, Wei JJ.
europepmc +1 more source
ABSTRACT Background and Aims Acute respiratory failure requiring intensive care is frequently accompanied by hemodynamic instability, necessitating vasoactive pharmacologic support, and elevated mortality. We aimed to develop and validate a machine learning model to stratify all‐cause in‐hospital mortality risk in ICU patients with respiratory failure ...
Mohammad Fathi +8 more
wiley +1 more source
The role of supraoptic hypothalamic arginine vasopressin neurons in aging-associated water balance and thermoregulatory deficits in male mice. [PDF]
Morones N +15 more
europepmc +1 more source

