Results 161 to 170 of about 27,910 (308)

Vasopressin Receptor [PDF]

, 2020
openaire   +1 more source

Dexamethasone Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Study Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest Trial (DANOHCA)

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background The inflammatory response to whole‐body ischemia, as seen in comatose survivors after out‐of‐hospital cardiac arrest (OHCA), is associated with increased morbidity and mortality. Early high‐dose dexamethasone may dampen the inflammatory response, which may diminish secondary brain damage and other organ injury and decrease mortality.
Jo B. Andreasen, Anders Morten Grejs, Simon Mölström, Lars P. K. Andersen, Sören Möller, Steffen Christensen, Henrik Schmidt, Jacob E. Møller, Martin A. S. Meyer, Jesper Kjærgaard, Alexander W. Erbs, Bodil S. Rasmussen, Christian Hassager   +12 more
wiley   +1 more source

Is thirst the missing physiological link between SGLT2 inhibitors and reduced nephrolithiasis risk? [PDF]

Clin Kidney J
Lombardi M, Beltrami P, Martini B.
europepmc   +1 more source

Linezolid‐induced lactic acidosis in critically ill patients: A multicentre study of incidence, severity and predictors

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2239-2249, July 2026.
Abstract Introduction Linezolid, a synthetic oxazolidinone for resistant gram‐positive infections, is generally associated with mild adverse effects such as gastrointestinal disturbances, but more serious reactions like lactic acidosis (LA) have also been reported.
Lina Naseralallah, Bodoor Aboujabal, Zahra Noureddine, Khaled Aboujabal, Somaya Koraysh   +4 more
wiley   +1 more source

Polygonatum cyrtonema Polysaccharides‐Derived Metabolic Meta Alleviates ALD via a Gut–Liver Axis–Mediated, Bifidobacterium pseudolongum–Driven Suppression of the AA Metabolism–MAPK Signaling Network

Food Frontiers, Volume 7, Issue 4, July 2026.
This study demonstrates that the hepatoprotective effect of Polygonatum cyrtonema polysaccharide (PCP) is mediated by its gut microbiota‐derived metabolome, which enriches Bifidobacterium pseudolongum, suppresses the gut–liver axis of AA metabolism, and inhibits hepatic MAPK signaling. ABSTRACT Polygonatum cyrtonema, a traditional Chinese medicinal and
Xingcai Gao, Qing Zhou, Baoting Liu, Jun Li, Jianhua Xie, Yi Chen, Chenxu Gong, Xiaobo Hu, Qiang Yu   +8 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

How important are quantum mechanical effects in controlling biological functions: Enzymes, electron transfer and bird navigation

Protein Science, Volume 35, Issue 7, July 2026.
Abstract In light of the centennial of the Schrödinger equation, this article addresses the popular idea that quantum mechanical effects play an important role in biological systems. We start by defining what is qualified as a quantum effect. We then clarify the idea that quantum mechanical tunneling is a crucial factor in enzyme catalysis.
Aoxuan Zhang, Arieh Warshel
wiley   +1 more source

Novel roles of GPCRs in the renal collecting duct. [PDF]

Physiology (Bethesda)
Kui MK, Zhang JJ, Pluznick JL.
europepmc   +1 more source

Vasopressin in cardiogenic shock: pathophysiology, clinical evidence, and therapeutic perspectives. [PDF]

ESC Heart Fail
Filomia S, Del Buono MG, Saponara G, d'Aiello A, Pedicino D, Moroni F, Abbate A, Sanna T.   +7 more
europepmc   +1 more source

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, Volume 105, Issue 1, Page 14-21, July 2026.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source