Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Ana Martín‐Sánchez +6 more
wiley +1 more source
SGLT2 Inhibitors as a Novel Therapeutic Strategy in SIADH-Induced Hyponatraemia: Emerging Evidence and Clinical Implications. [PDF]
Kamran N, Mohammad M.
europepmc +1 more source
A 3D‐printed screening‐to‐reactor platform enabled rapid optimisation of ADH‐200 immobilisation using imidazolium‐based supported ionic liquid phases. High‐throughput evaluation in 96‐well plates identified methyl‐imidazolium formulations as the best‐performing supports, which were directly translated into honeycomb continuous‐flow reactors.
Simone Marchetti +6 more
wiley +1 more source
Vasopressin Receptor Antagonists. Therapeutic Efficacy of Vasopressin Receptor Antagonists.
ISHIKAWA, San-e, SAITO, Toshikazu
openaire +2 more sources
Managing sepsis in the era of precision medicine: a narrative review. [PDF]
Yong HJ, Kim SM, Kim D.
europepmc +1 more source
The role of vasopressin in trauma resuscitation: a protocol of a systematic review and meta-analysis of randomized and observational studies. [PDF]
Yousefi MR, Ghasemian M, Paydar S.
europepmc +1 more source
Let There be Light! Light as an Engine and Regulator in Synthetic Cells
Cells are out‐of‐equilibrium systems that regulate their spatiotemporal features. In biomimetic synthetic cells, light offers a unique way for energizing and regulating events in space and time. This review explores the implementation of light‐responsive tools in synthetic cells to replicate biological functions and enable new bioinspired behaviors ...
Matthew E. Allen +5 more
wiley +1 more source
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source
Hormonal Contraception and Vestibular Disorders: A Narrative Review of Clinical Implications, Diagnostic Challenges, and Evidence Gaps. [PDF]
Castillo-Bustamante M +2 more
europepmc +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source

