Results 171 to 180 of about 27,910 (308)

Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Ana Martín‐Sánchez   +6 more
wiley   +1 more source

3D‐Printed Platforms for Enzyme Immobilisation Screening and Direct Translation into Continuous‐Flow Biocatalysis

open access: yesChemSusChem, Volume 19, Issue 12, 26 June 2026.
A 3D‐printed screening‐to‐reactor platform enabled rapid optimisation of ADH‐200 immobilisation using imidazolium‐based supported ionic liquid phases. High‐throughput evaluation in 96‐well plates identified methyl‐imidazolium formulations as the best‐performing supports, which were directly translated into honeycomb continuous‐flow reactors.
Simone Marchetti   +6 more
wiley   +1 more source

Let There be Light! Light as an Engine and Regulator in Synthetic Cells

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 24, 8 June 2026.
Cells are out‐of‐equilibrium systems that regulate their spatiotemporal features. In biomimetic synthetic cells, light offers a unique way for energizing and regulating events in space and time. This review explores the implementation of light‐responsive tools in synthetic cells to replicate biological functions and enable new bioinspired behaviors ...
Matthew E. Allen   +5 more
wiley   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

open access: yesAdvanced Functional Materials, Volume 36, Issue 44, 1 June 2026.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang   +7 more
wiley   +1 more source

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