Results 211 to 220 of about 580,482 (298)

Pituitary Neurolobectomy induces sustained hypotension in male Wistar rats and normalizes blood pressure in male spontaneously hypertensive rats. [PDF]

open access: yesPhysiol Rep
Villanueva-Rodríguez GM   +6 more
europepmc   +1 more source

Severe Hypernatraemia Secondary to Adipsia Associated With a Pituitary Macroadenoma in a Dog: A Case Report

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Severe hypernatraemia (Na+ 192 mmol/L) secondary to adipsia was successfully managed through gradual sodium correction, close monitoring and assisted water supplementation in a dog with a pituitary macroadenoma. No neurologic complications occurred during correction, and serum sodium concentrations remained stable for 9 months. This case highlights the
Gyo‐Bin Choo   +4 more
wiley   +1 more source

Source‐Independent Enrichment of Light Lanthanides: Microbial Mobilization, Selective Uptake, and Intracellular Storage

open access: yesEnvironmental Microbiology, Volume 28, Issue 9, September 2026.
Only light lanthanides facilitate lanthanide‐dependent methylotrophy. In Beijerinckiaceae bacterium RH AL1, light lanthanides are enriched from diverse sources, including poorly soluble minerals, through a multilayered process involving mobilisation, selective uptake, and intracellular periplasmic storage.
Linda Gorniak   +9 more
wiley   +1 more source

Impaired Renal Base Excretion in Secretin Receptor Knock‐Out Mice During Prolonged Base‐Loading

open access: yesActa Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT Aim Secretin was recently found to play a pivotal role in the renal adaptation to acute base excess. Here, secretin increases pendrin‐dependent HCO3− secretion from the beta‐intercalated cells in the cortical collecting ducts. Whether secretin and its receptor play a role during prolonged base‐loading remains unknown.
Tobias Jensen   +10 more
wiley   +1 more source

Leveraging Healthy Volunteers for Anticancer Drug Clinical Pharmacology Studies: A Review Article Featuring Futibatinib as an Example

open access: yesClinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Early clinical development of anticancer drugs traditionally focused on exploring candidate treatments in patients. For instance, due to their cytotoxic action, administration of chemotherapies to healthy volunteers (HVs) for evaluation of their pharmacokinetic profiles was not considered feasible nor ethical from a safety and tolerability ...
Aernout D. van Haarst   +5 more
wiley   +1 more source

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