Results 221 to 230 of about 50,162 (238)

Human vascular vasopressin receptors: analysis with selective vasopressin receptor antagonists.

The Journal of Pharmacology and Experimental Therapeutics, 1986
The vascular activity of arginine vasopressin (AVP) and selective AVP receptor antagonists was investigated in isolated arterial ring segments from human superior mesenteric arteries. AVP elicited a potent and concentration-dependent contraction in human mesenteric arterial rings with an EC50 value of 2.01 X 10(-9) M.
E H, Ohlstein, B A, Berkowitz
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Vasopressin Receptors in Voiding Dysfunction

2011
Arginine vasopressin (AVP), also known as vasopressin or anti-diuretic hormone, is a neuropeptide produced in the hypothalamus. It is primarily responsible for osmoregulation and thus maintains body fluid homeostasis. It is also a potent vasoconstrictor, may have a role in higher cognitive functions and affects metabolism.
Sailaja Pisipati, Hashim Hashim
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Arrestin Effects on Internalization of Vasopressin Receptors

Molecular Pharmacology, 2001
Arrestins have been shown to facilitate the recruitment of G protein-coupled receptors to the clathrin-coated vesicles that mediate their internalization. After (8)Arg-vasopressin-induced internalization, the human V2 vasopressin receptor failed to recycle to the cell surface, whereas the vasopressin type 1a receptor (V1a) subtype did.
D. Bowen Pidgeon, INNAMORATI, Giulio, H. M. Sadeghi, M. Birnbaumer   +3 more
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Vasopressin Receptors

2009
This chapter focuses on the expression and functions of arginine vasopressin receptors (AVPRs) throughout the body, but particularly in the brain. In order to place receptor activity into a physiologically and behaviorally relevant context, it begins with a brief overview of the hormones arginine vasopressin (AVP) and oxytocin (OT), which serve as ...
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Chronic Blockade of Vasopressin Receptors in Rats

Journal of Cardiovascular Pharmacology, 1986
Chronic i.v. administration of a competitive antagonist of arginine-vasopressin (AVP), d(CH2)5-D-Tyr(Et)-VAVP, in Sprague-Dawley rats induced only a transient diabetes insipidus (DI)-like state. Water excretion and intake were markedly increased on the first day of administration but subsequently reverted to normal. A similar response to the antagonist
Hofbauer, K. G., Mah, S. C., Opperman, J. R.   +2 more
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Upregulation of V1a vasopressin receptors by glucocorticoids

American Journal of Physiology-Endocrinology and Metabolism, 1992
WRK1 cells (a rat mammary tumor cell line) exhibit a vasopressinergic receptor of V1a subtype tightly coupled to phospholipase C. Addition of dexamethasone to the culture medium principally potentiated the vasopressin-sensitive accumulation of inositol phosphates and to a lesser extent the NaF-sensitive phospholipase C activity.
A. Duvoid, Ginette Devilliers, Gilles Guillon, P. Colson, Marie-Noëlle Balestre, J. Ibarondo   +5 more
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Molecular Modeling of Interaction of the Vasopressin Analogs with Vasopressin and Oxytocin Receptors

QSAR & Combinatorial Science, 2003
AbstractIn this study the interaction of seven new analogs of arginine vasopressin (AVP) substituted in position 2 or 3 with 1‐aminocyclohexanecarboxylic acid (Acc) with the vasopressin (VP) and oxytocin (OT) receptors (V1aR, V2R and OTR) is described. All peptides were synthesized and tested in bioassays for pressor and antidiuretic activities.
Rajmund Kaźmierkiewicz, Bernard Lammek, Rafał Ślusarz, Magdalena J. Ślusarz   +3 more
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Vasopressin antagonists block peripheral as well as central vasopressin receptors

Pharmacology Biochemistry and Behavior, 1984
The aim of the present study was to differentiate between the postulated central behavioral effects of vasopressin and its pressor response, which is mainly mediated by peripheral vascular receptors. Thus, the interaction between the vasopressor antagonists dPTyr(Me)AVP (AAVPa) and d(CH2)5Tyr(Me)AVP (AAVPb) with the effects of [Arg8]vasopressin (AVP-(1-
David de Wied, Wybren de Jong, O. Gaffori, Jan M. van Ree   +3 more
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Interaction of a vasopressin antagonist with vasopressin receptors in the septum of the rat brain

Synapse, 1988
AbstractThe ability of d(CH2)5‐Tyr(Me)‐arginine‐8‐vasopressin, an antagonist of peripheral pressoric (V1‐type) vasopressin receptors, to label vasopressin binding sites in the septum of the rat brain was evaluated. Using crude membrane preparations from the septum, 3H‐arginine‐8‐vasopressin (AVP) specifically labels a single class of binding sites with
Daniel M. Dorsa, Patricia Szot, Patricia Szot, Michelle D. Brot, Michelle D. Brot, Margaret A. Miller, Margaret A. Miller, Kathleen M. Meyers, Kathleen M. Meyers, Linda M. Shewey, Linda M. Shewey   +10 more
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Vasopressin: Mechanisms of Receptor Activation

1983
Publisher Summary Vasopressin exerts a large variety of biological effects such as increased glycogenolysis and neoglucogenesis by liver cells and increased corticotrophin release by the adenohypophysis. This chapter presents an overview of the available pharmacological and biochemical data on vasopressin receptors in mammals.
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