Results 251 to 260 of about 580,482 (298)

Vasopressin Receptors

Trends in Endocrinology & Metabolism, 2000
The biological effects of arginine vasopressin (AVP) are mediated by three receptor subtypes: the V1a and V1b receptors that activate phospholipases via Gq/11, and the V2 receptor that activates adenylyl cyclase by interacting with Gs. Isolation of the cDNAs encoding the V1a and V1b receptor subtypes explained the tissue variability of V1 antagonist ...
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Palmitoylation of the V2 Vasopressin Receptor

Molecular Pharmacology, 1997
Palmitoylation of the V2 vasopressin receptor (V2R) and its functional role were investigated in transfected cells. Palmitoylation was assessed by incubating transfected cells with [3H]palmitic acid and immunoprecipitating the receptor with an antibody raised against a portion of the third intracellular loop of V2R.
H. M. Sadeghi, INNAMORATI, Giulio, M. Dagarag, M. Birnbaumer   +3 more
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Genetics of vasopressin receptors

Current Hypertension Reports, 2004
Membrane receptors that couple to guanine nucleotide binding protein (GPCRs) represent one of the largest families of proteins in the genome. Because of their universal distribution and multiple actions, genetic variations of GPCRs are associated with various human diseases.
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Vasopressin Receptor Antagonists

Current Hypertension Reports, 2015
Arginine vasopressin (AVP) is the principal hormone involved in regulating the tonicity of body fluids. Less appreciated is the role that AVP plays in a variety of other physiologic functions including glucose metabolism, cardiovascular homeostasis, bone metabolism, and cognitive behavior.
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Human platelet vasopressin receptors

Life Sciences, 1982
Specific saturable binding of 125I-arginine-vasopressin to human platelets is described. For ten normal volunteers the mean (+/- S.D.) KD is 5.6 nM (+/- 2.1) and the mean (+/- S.D.) Bmax is 115 fmoles/mg protein (+/- 30). Association studies indicate that equilibrium is reached after 90 minutes on ice.
W H, Berrettini, R M, Post, E K, Worthington, J B, Casper   +3 more
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Vascular vasopressin receptors

General Pharmacology: The Vascular System, 1988
1. Vascular vasopressin receptors are understood because of the specific application of each major technical advance in pharmacology; this review shows that isolated organs, whole animal preparations, hormone synthesis, radioligand binding, and human studies have all played their part. 2. Even so, neither vascular vasopressin receptor heterogeneity nor
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V2 vasopressin receptor mutations

2020
V2 vasopressin receptor (V2R) is a member of the G protein-coupled receptor (GPCR) family in which many disease-causing mutations have been identified and thus generated much interest. Loss-of-function V2R mutations cause nephrogenic diabetes insipidus (NDI) whereas gain-of-function mutations cause nephrogenic syndrome of inappropriate antidiuresis ...
Noriko, Makita, Katsunori, Manaka, Junichiro, Sato, Taroh, Iiri   +3 more
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Vasopressin Receptors in Voiding Dysfunction

2011
Arginine vasopressin (AVP), also known as vasopressin or anti-diuretic hormone, is a neuropeptide produced in the hypothalamus. It is primarily responsible for osmoregulation and thus maintains body fluid homeostasis. It is also a potent vasoconstrictor, may have a role in higher cognitive functions and affects metabolism.
Sailaja, Pisipati, Hashim, Hashim
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Human vascular vasopressin receptors: analysis with selective vasopressin receptor antagonists.

The Journal of Pharmacology and Experimental Therapeutics, 1986
The vascular activity of arginine vasopressin (AVP) and selective AVP receptor antagonists was investigated in isolated arterial ring segments from human superior mesenteric arteries. AVP elicited a potent and concentration-dependent contraction in human mesenteric arterial rings with an EC50 value of 2.01 X 10(-9) M.
E H, Ohlstein, B A, Berkowitz
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Vasopressin: Mechanisms of Receptor Activation

1983
Publisher Summary Vasopressin exerts a large variety of biological effects such as increased glycogenolysis and neoglucogenesis by liver cells and increased corticotrophin release by the adenohypophysis. This chapter presents an overview of the available pharmacological and biochemical data on vasopressin receptors in mammals.
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