Results 261 to 270 of about 2,349,142 (333)
Microbial Biotechnology, Volume 18, Issue 8, August 2025.We used reverse genetic engineering of the gas‐fermenting model‐acetogen Clostridium autoethanogenum to recover enhanced phenotypes from autotrophic adaptive laboratory evolution. Reverse‐engineered strains were characterised at systems level and bioinformatics suggest that the targeted genes may be involved in overlapping regulatory networks ...
Henri Ingelman +2 more
wiley +1 more source
The current use of vasoactive agents in cardiogenic shock related to myocardial infarction and acute decompensated heart failure. [PDF]
Am Heart J PlusBecerra AF +4 more
europepmc +1 more source
Artificial Organs, Volume 49, Issue 8, Page 1249-1264, August 2025.High‐risk cardiac patients may benefit from timely temporary mechanical circulatory support (tMCS) implantation to provide perioperative hemodynamic stabilization and circulatory support, thus enabling them to undergo life‐saving thoracic surgery. CPB: cardiopulmonary bypass; IABP: intra‐aortic balloon pump; tMCS: temporary mechanical circulatory ...
Viviana Teresa Agosta +4 more
wiley +1 more source
Advancing antihypertensive drug development
British Journal of Pharmacology, Volume 182, Issue 15, Page 3389-3410, August 2025.Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu +5 more
wiley +1 more source
Sex differences in structural and receptor mRNA expression in the ventral anterior cingulate cortex and a potential role of perineuronal nets in monogamous pair bond establishment (Peromyscus californicus). [PDF]
Biol Sex DifferMalone CL +7 more
europepmc +1 more source
Hyponatremia: A role for vasopressin receptor antagonists?
Journal of Anaesthesiology Clinical Pharmacology, 2018 openaire +4 more sources
British Journal of Pharmacology, Volume 182, Issue 16, Page 3695-3709, August 2025.Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio +5 more
wiley +1 more source
Impact of perinatal hypertonic NaCl access on adult offspring's sodium intake and angiotensin and vasopressin systems under hypertension model. [PDF]
Sci RepPorcari CY +5 more
europepmc +1 more source
The DCIDE framework: systematic investigation of evolutionary hypotheses, exemplified with autism
Biological Reviews, Volume 100, Issue 4, Page 1484-1511, August 2025.ABSTRACT Evolutionary explanations of mental disorders are a longstanding aim of evolutionary psychiatry, but have suffered from complexities including within‐disorder heterogeneity and environmental effects of contemporary societies obscuring possible ancestral functions.
Adam D. Hunt, Adrian V. Jaeggi
wiley +1 more source