Results 271 to 280 of about 4,403,902 (351)

Shaping viral immunotherapy towards cancer-targeted immunological cell death. [PDF]

Front Oncol
Isaeva AS, Trujillo Yeriomenko AD, Idota E, Volodina SI, Porozova NO, Bezsonov EE, Malogolovkin AS.   +6 more
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Single Amino Acid Residue W33 of <i>tva</i> Receptor Is Critical for Viral Entry and High-Affinity Binding of Avian Leukosis Virus Subgroup K. [PDF]

Viruses
Gáliková E, Přikryl D, Prost S, Kučerová D, Trejbalová K, Hejnar J.   +5 more
europepmc   +1 more source

Biomolecular Condensates as Emerging Biomaterials: Functional Mechanisms and Advances in Computational and Experimental Approaches

Advanced Materials, EarlyView.
Integration of computational and experimental approaches for deciphering the underlying mechanism of biomolecular condensates and potential biomaterials design (Created in Biorender. Raza, Z. (2025) https://BioRender.com/irgmeqi). Abstract Biomolecular condensates, a ubiquitous class of biomaterials found in living cells, have been shown to be ...
Qiang Zhu, Zahra Raza, Dzung Do‐Ha, Emma De Costa, Pavlina Sasheva, Luke McAlary, Hadi Mahmodi, Warwick P. Bowen, Lezanne Ooi, Irina Kabakova, Haibo Yu   +10 more
wiley   +1 more source

The function and mechanism of protein acylation in the regulation of viral infection. [PDF]

Virulence
Song L, Wei Z, Shang P, Hu S, Chen L, Niu L, Wang Y, Gan M, Shen L, Zhu L, Zhao Y.   +10 more
europepmc   +1 more source

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

Advanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang, Yanpu He, Allison Madow, Huaiyao Peng, Mirielle Griffin, Jifa Qi, Mantao Huang, Heather Amoroso, Riley Abrashoff, Nimrod Heldman, Angela M. Belcher   +10 more
wiley   +1 more source

Innate Immune Response to Powassan Virus Infection: Progress Toward Infection Control. [PDF]

Vaccines (Basel)
Kayesh MEH, Kohara M, Tsukiyama-Kohara K.   +2 more
europepmc   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

Advanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost, Annina Stuber, Kongchang Wei, Marine de Lapeyrière, Ke Yang, Valentin Gantenbein, Salvador Pané, Ivan Corbeski, Katharina Maniura‐Weber, Nako Nakatsuka   +9 more
wiley   +1 more source

Genome-wide CRISPR/Cas9 screen identifies host factors for Newcastle disease virus replication. [PDF]

Poult Sci
Tian J, Wang Y, Zhou Z, Li Y, Chang C, Meng F, Shi W, Li H, Wang W, Wei Q, Liu H, Yang Z, Xiao S.   +12 more
europepmc   +1 more source