Results 11 to 20 of about 2,009,256 (317)

Opioids and Their Receptors [PDF]

, 2020
The interest in opioids such as morphine, the prototypical opioid ligand, has been maintained through the years. The identification of endogenous opioids and their receptors (mu, delta, kappa, and nociceptin), molecular cloning, and the elucidation of ...

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Distinct pharmacological and functional properties of NMDA receptors in mouse cortical astrocytes [PDF]

, 2011
Background and purpose Astrocytes of the mouse neocortex express functional NMDA receptors which are not blocked by Mg2+ions. However, study of the pharmacological profile of glial NMDARs and their subunit composition is far from complete ...
Lalo, Ulyana, Pankratov, Yuriy, Palygin, Oleg, Oleg Palygin, Ulyana Lalo, Yuriy Pankratov   +5 more
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Identification of a domain which affects kinetics and antagonistic potency of clozapine at 5-HT3 receptors. [PDF]

, 2009
The widely used atypical antipsychotic clozapine is a potent competitive antagonist at 5-HT(3) receptors which may contribute to its unique psychopharmacological profile. Clozapine binds to 5-HT(3) receptors of various species.
Gerhard Rammes, Caroline Nothdurfter, Tanasic, S., Rammes, G., Rupprecht, R., Eisensamer, Brigitte, Zieglgänsberger Walter, Christine Hosp, Tanasic, Sascha, Hosp Christine, Walter Zieglgänsberger, Rupprecht Rainer, Rammes, Gerhard, Sascha Tanasic, Hosp, C., Rammes Gerhard, Nothdurfter, C., Tanasic Sascha, Rupprecht, Rainer, Nothdurfter Caroline, Brigitte Eisensamer, Eisensamer, B., Zieglgänsberger, Walter, Zieglgänsberger, W., Hosp, Christine, Rainer Rupprecht, Nothdurfter, Caroline, Eisensamer Brigitte   +27 more
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Characterisation of bovine leukocyte Ig-like receptors

, 2012
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Laing Ken, Martin Vordermeier, John Trowsdale, Singh Mahavir, Philip Butcher (173962), Allen Rachel L., Ken Laing, Laing, K, Butcher, P, Mahavir Singh, Des C Jones, Butcher, Philip, Bhuju, S, Ken Laing (173955), Vordermeier, M, Singh, Mahavir, Jones, DC, Trowsdale, John, Mahavir Singh (70735), Rachel L Allen, Hogan, Louise, Trowsdale, J, Hogan Louise, Vordermeier Martin, Hogan, L, Philip Butcher, Singh, M, Allen, RL, Des C. Jones (173949), Louise Hogan (173942), John Trowsdale (1225), Martin Vordermeier (108962), Trowsdale John, Vordermeier, Martin, Allen, Rachel L, Jones Des C., Sabin Bhuju, Laing, Ken, Bhuju Sabin, Sabin Bhuju (107606), Rachel L. Allen (173972), Jones, Des C, Bhuju, Sabin, Louise Hogan, Butcher Philip   +44 more
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Emerging key roles for P2X receptors in the kidney [PDF]

, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides.
Peppiatt-Wildman, Claire M., Peppiatt-Wildman, C. M., Wildman, S. S., R. E. Birch, C. M. Peppiatt-Wildman, Scott S Wildman, Schwiebert, E. M., Wildman, Scott S.P., E. M. Schwiebert, S. S. Wildman, Birch, R. E.   +10 more
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Molecular Perspectives on Prostate Cancer: The Role of microRNAs in Androgen Receptor Regulation

Receptors
Prostate cancer (PCa) is the most prevalent cancer among men globally. In addition to environmental risk factors, genetic factors play a crucial role in its development and progression, highlighting the regulation of key genes as an essential aspect. The
Asbiel Felipe Garibaldi-Ríos, Alicia Rivera-Cameras, Luis E. Figuera, Guillermo Moisés Zúñiga-González, Belinda Claudia Gómez-Meda, José Elías García-Ortíz, Martha Patricia Gallegos-Arreola   +6 more
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P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]

, 2008
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
King, Brian F., Wildman, Scott S.P.
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Systemic Chronic Inflammation: Integrative Strategies for Health Improvement and Prevention of Inflammatory Receptor Overexpression

Receptors
The body’s physiology during physical injuries and diseases depends heavily on the function of acute inflammation. On the other hand, many variables, including iatrogenic, immune system deficiencies, lifestyle, and social and environmental factors, are ...
Abraham Puga-Olguín, María Fernanda Hernández-Hernández, Rafael Fernández-Demeneghi, Carlos Iván López-Miranda, Luis Ángel Flores-Aguilar   +4 more
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Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors.

, 2015
GABAA receptors are important for inhibition in the CNS where neurosteroids and protein kinases are potent endogenous modulators. Acting individually, these can either enhance or depress receptor function, dependent upon the type of neurosteroid or ...
Adams, JM, Thomas, P, Adams, Joanna M., Thomas, Philip, Smart, Trevor G., Smart, TG   +5 more
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Unraveling the Role of CHRNA6, the Neuronal α6 Nicotinic Acetylcholine Receptor Subunit

Receptors
The increased prevalence of electronic cigarettes, particularly among adolescents, has escalated concerns about nicotine addiction. Nicotine, a potent psychostimulant found in tobacco products, exerts its effects by interacting with nicotinic ...
Yasamin Hajy Heydary, Emily M. Castro, Shahrdad Lotfipour, Frances M. Leslie   +3 more
doaj   +1 more source