Results 41 to 50 of about 503,937 (288)

An analysis of household transportation spending during the 2007-2009 US economic recession [PDF]

open access: yes, 2014
The recent economic recession in the United States led to widespread destruction of jobs, home foreclosures, credit freeze and to creditor repossessions of key assets such as personal cars. Our objective is to empirically assess transportation conditions
Mallon-Keita, Yaye   +1 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Employment During the 2001–2003 Recovery [PDF]

open access: yes, 2005
This background paper examines job growth following the 2001 recession. After declining by about 1.6 million jobs during that recession, employment fell by more than an additional million jobs in the first 18 months following the end of the recession ...
U.S. Congressional Budget Office
core   +1 more source

Combined resection–recession versus combined recession–retroequatorial myopexy of medial rectus muscles for treatment of near-distance disparity Esotropia

open access: yesClinical Ophthalmology, 2017
Manar A Ghali Ophthalmology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt Purpose: To compare and evaluate the efficacy of two different surgical techniques for the treatment of near-distance disparity esotropia; combined ...
Ghali MA
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Unemployment in the Great Recession: single parents and men hit hard [PDF]

open access: yes, 2011
This brief discusses the sweeping impact the Great Recession has had on Americans, particularly men, single parents, young adults, and people with less education.
Bean, Jessica A.   +2 more
core   +1 more source

Unemployment in the great recession [PDF]

open access: yes, 2013
This paper studies the responses of unemployment in Germany, the United States and Britain to the Great Recession of 2008-09 by making use of Beveridge curve analysis, and in the entire OECD with other techniques.
Pissarides, Christopher A.
core   +2 more sources

THE GERMAN ECONOMY: RECESSION OF 2024 AND CHALLENGES FOR 2025 [PDF]

open access: yesНаучно-аналитический вестник Института Европы РАН
This article analyzes Germany’s economic developments in 2024, which largely determine the prospects for 2025. The German economy has been in a recession for the second consecutive year. The author examines the key macroeconomic indicators as well as the
Vladislav B. Belov
doaj   +1 more source

ECONOMIC POLICY TO OVERCOME STAGNATION AFTER THE FINANCIAL CRISIS

open access: yesВестник университета, 2021
The article considers the downward spiral of deflation, its causes and consequences. The paper discusses the compression of aggregate demand and the subsequent recession.
V. D. Kuligin
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

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