Results 21 to 30 of about 8,193,304 (254)
Éditorial - La recherche en français en sciences de l'information au Canada et Partnership
Partnership vise à encourager la dissémination de la production scientifique francophone et anglophone canadienne en bibliothéconomie et en sciences de l’information. Ce numéro met de l’avant la recherche en français avec trois articles.
Éthel Gamache
doaj +1 more source
Une recherche collaborative pour analyser la conférence Paris Climat 2015 : le projet ClimaCOP [PDF]
Le projet ClimaCOP propose une analyse collaborative de la COP 21 qui aura lieu à Paris en décembre 2015. Il s’articule autour d’un collectif multidisciplinaire d’une trentaine de chercheurs en sciences sociales, spécialistes des ...
Foyer Jean, Morena Édouard
doaj +1 more source
Quelques informations anonymes concernant les 129 candidatures au premier prix science ouverte du logiciel libre de ...
Le Berre, Daniel
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Recherche littéraire / Literary Research [PDF]
As the annual peer-reviewed publication of the International Comparative Literature Association (ICLA), Recherche littéraire / Literary Research is an Open Access journal published by Peter Lang.
core +5 more sources
As a tribute to the thinking of Jean-Claude Gillet, this article aims to make accessible in the English language some of the notions of sociocultural community development and its function developed by this author in relation to their testing during a ...
Sylvia Garcia Delahaye +2 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

