Results 241 to 250 of about 524,632 (318)

Microvascular Toe-to-thumb Transfer After High-voltage Electrical Burn: A Case Series and a Narrative Review. [PDF]

Plast Reconstr Surg Glob Open
Bregman D, Stanton E, Ebner P, Howell AC, Mohammed S, Stevanovic M.   +5 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Epigenetic programming by H3K23ac defines lineage fate of Meg3⁺ haematopoietic stem cells and drives immune ageing. [PDF]

Nat Cell Biol
Wei N, Zhan H, Deng Y, Liu M, Xiao Y, Gong Y, Wang X, Guan P, Lou X, Xie Y, Wang Y, Li Z, Dai L, Hu H, Zhang H.   +14 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

From laparoscopy to robotics in living donor hepatectomy: a systematic review and meta-analysis of comparative outcomes. [PDF]

J Robot Surg
Al Sayed M, Albashier M, Altabbaa H, Omar Saleh A, Hadhoud AM, Hussein MA, Aljarrah AY, Abdelrazek MM, Bakhiet M.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A New Lifeline: Feasibility and Outcomes of Altruistic Donor Programs in Living-Donor Liver Transplantation, A Single Saudi Center Experience. [PDF]

Ann Transplant
Zidan A, Gadour E, Tawfiq SZ, Kuriry H, Bader RM, Momani H, Saleh Y, Sengupta B, Khan I, Al Faraj NH, Alkhiliwi A, Alraddadi I, Alshammari N, Abdullah RA, Tawfeeq M, Obeid M, Bel'eed-Akkari K, Alsaghier MI, Alqahtani M.   +18 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Donor Microbiota Metabolic Capacity Determines Engraftment Dynamics and Modulates Gut–Brain Signaling in Recipient Mice

Farzi A, Durdevic M, Fellendorf F, Schimmel P, Kuehnast T, Bukowski-Thall G, Gorkiewicz S, Ip CK, Habisch H, Fischer S, Mörkl S, Wagner-Skacel J, Bengesser S, Lenger M, Dalkner N, Hoegenauer C, Madl T, Moissl-Eichinger C, Gorkiewicz G, Reininghaus E.   +19 more
europepmc   +1 more source

Effort produces after-effects costly for others but valued for self. [PDF]

Elife
Zheng Y, Tang R.
europepmc   +1 more source