Results 111 to 120 of about 482,932 (313)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Reciprocal peer coaching: a constructivist methodology for enhancing student resilience and psychological well being [PDF]

open access: yes, 2017
Background: Universities have become increasingly reliant upon peer assisted learning as a valuable teaching and learning strategy in higher education. Reciprocal peer coaching (RPC) is a form of independent peer assisted learning that has an important ...
Matthewman, L.J.
core  

Comparison of Apical Transportation with Using Hand, Reciprocal and Race Instrumentation

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2011
BACKGROUND AND OBJECTIVE: Mechanical preparation of root canal system is an important objective of root canal therapy. Many rotary devices have been produced to decrease instrumentation time and improve its quality.The purpose of this study was to ...
Disfani R, Moradi S, Afkhami Jedi F
doaj  

Conversion: non-réciproque – réciproque. Variantes syntaxiques

open access: yesStudia Romanica Posnaniensia, 2010
The present paper is devoted to the concept of reciprocity and to reciprocal expressions, which are divided into two main classes. Those belonging to the first of them signify reciprocity on their own, i.e. without any additional reciprocal markers.
Mikołaj Nkollo
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Another experimental look at reciprocal behavior: indirect reciprocity [PDF]

open access: yes
This paper highlights a new social motivation, the indirect reciprocity, through a three-player dictator-ultimatum game. Player 2 has the opportunity to reward or punish indirectly the player 1 by inciting – with her offer - player 3 to accept or to ...
Bonein Aurélie, Serra Daniel
core  

Knowledge structures and motivation to learn: Reciprocal effects [PDF]

open access: yes, 2000
Historically, research has separately investigated the role of prior knowledge structure and the importance of motivation in learning engagement. Limited attention has been given to the reciprocal effects of these two influences.
Nan Bahr   +4 more
core  

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