Results 261 to 270 of about 452,570 (334)

Reciprocal translocation and the Philadelphia chromosome

Human Genetics, 1978
We examined metaphases from three patients with chronic myeloid leukaemia and a typical Philadelphia chromosome with one chromosome 9 as the recipient to determine whether the 9q+22q- translocation is reciprocal. Good quality G-banded photographs of the chromosomes concerned were subjected to light absorption density analysis.
J L, Watt, B M, Page
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“Understanding Adam” Multiple Reciprocal Translocations

Journal of Perinatal & Neonatal Nursing, 2009
This article presents a case review of a newborn diagnosed with a complex chromosomal rearrangement, as demonstrated through a painted chromosomal analysis. This infant presented with multiple dysmorphology including cutis aplasia, multiple ocular malformations, bilateral cleft lip and palate, and postnatal hydrocephaly. A chromosomal analysis revealed
Carie E, Linder, Xianglan, Lu, Young Mi, Kim, Shibo, Li, Jose, Pineda   +4 more
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Autosomal Reciprocal Translocations

2011
Abstract RECIPROCAL TRANSLOCATIONS ARE COMMON, and every counselor can expect to see translocation families. The usual form is the simple, or two-way, reciprocal translocation: only two chromosomes, usually autosomes, are involved, with one breakpoint in each. It is this category we consider in this chapter.
R. J. McKinlay Gardner, Grant R. Sutherland, Lisa G. Shaffer   +2 more
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Balanced reciprocal translocation mosaicism: How frequent?

American Journal of Medical Genetics, 1995
AbstractWe describe 2 cases of balanced reciprocal translocation (BRT) mosaicism. The frequency of this aberration in the population referred to our laboratory was determined and compared to those frequencies reported in the literature by other clinical cytogenetics laboratories.
K E, Opheim, A, Brittingham, D, Chapman, T H, Norwood   +3 more
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Segregation analysis in reciprocal translocation carriers

American Journal of Medical Genetics, 1984
AbstractSegregation analysis of the offspring of balanced translocation carriers was performed on 327 pedigrees collated from published sources and personal communications. Correction was made for bias of ascertainment. Translocations studied involved chromosome arms 1p, 4q, 6p, 6q, 7p, 8p, 10p, 10q, 11q, 14q, 16q, and 17p.
D L, Petrosky, D S, Borgaonkar
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Reciprocal or nonreciprocal human chromosome translocations?

Human Genetics, 1977
Two carriers of a balanced translocation, one paternal t(9q-;13p+) and one maternal t(3q-;15p+), were studied cytogenetically with selective silver staining to localize more precisely the break points on the short arms of the two acrocentric chromosomes involved.
I, Hansmann, C, Wiedeking, T, Grimm, J, Gebauer   +3 more
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Autosomal reciprocal translocations and 13/14 translocations: A population study

Clinical Genetics, 1976
Fifteen children with autosomal reciprocal translocations were found in an incidence study of chromosome aberrations among 11,148 consecutively liveborn children in a Danish Maternity Hospital (1.34 per 1,000).The segregation rate of the balanced forms was 60 % and that of unbalanced forms 4 %; the frequency of familial cases was 73 %.
J, Nielsen, K, Rasmussen
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Partners with reciprocal translocations: genetic counseling for the ‘double translocation’

Clinical Genetics, 1998
SV at age 2 years presented with multiple congenital anomalies including an absent left kidney, anal stenosis, vertebral abnormalities, partial sacral agenesis, microcephaly, dysmorphic facial features, growth deficiency, and developmental delay. She was found to have a complex chromosomal rearrangement derived from balanced translocations in each ...
L, Cook, J K, Hartsfield, G H, Vance
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RECIPROCAL TRANSLOCATIONS IN SORGHUM VULGARE

Canadian Journal of Genetics and Cytology, 1963
Endrizzi and hilorgan ( 1955) reported the occurrence of reciprocal translocations in Sorghz~77jl m ~ l g a r e but did not examine pachynema configurations. The present study deals with cytological observations at prophase of meiosis, including pachynema, of three reciprocal translocations obtained by Haensel (1960) after gamma irradiation of the ...
C. C. Huang, J. G. Ross, H. D. Haensel
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Lack of reciprocal translocations in carcinomas

Cancer Genetics and Cytogenetics, 1986
Among the varied structural chromosomal aberrations present in the common forms of carcinoma, reciprocal translocations generally appear to be lacking. Although the breakpoints may be variable, the chromosomal changes nevertheless commonly result in the loss or gain of particular chromosomal segments. The possible implications of these observations are
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