Results 61 to 70 of about 483,022 (266)

Complex Variant t(9;22) Chromosome Translocations in Five Cases of Chronic Myeloid Leukemia

Advances in Hematology, 2009
The Philadelphia (Ph1) chromosome arising from the reciprocal t(9;22) translocation is found in more than 90% of chronic myeloid leukemia (CML) patients and results in the formation of the chimeric fusion gene BCR-ABL.
Ana Valencia, José Cervera, Esperanza Such, Eva Barragán, Pascual Bolufer, Oscar Fuster, Rosa Collado, Jesús Martínez, Miguel A. Sanz   +8 more
doaj   +1 more source

Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment [PDF]

, 2009
Background: t(9;22) is a balanced translocation, and the chromosome 22 breakpoints (Philadelphia chromosome – Ph+) determine formation of different fusion genes that are associated with either Ph+ acute lymphatic leukemia (Ph+ ALL) or chronic myeloid ...
Henschler, Reinhard, Moore, Malcolm A. S., Oancea, Claudia, Ruthardt, Martin, Zheng, Xiaomin   +4 more
core   +3 more sources

Signal Recognition Particle (SRP) and SRP Receptor: A New Paradigm for Multistate Regulatory GTPases [PDF]

, 2009
The GTP-binding proteins or GTPases comprise a superfamily of proteins that provide molecular switches in numerous cellular processes. The “GTPase switch” paradigm, in which a GTPase acts as a bimodal switch that is turned “on” and “off” by external ...
Schmid, Sandra L., Shan, Shu-ou, Zhang, Xin   +2 more
core   +2 more sources

Accumulation of numerical and structural chromosome imbalances in spermatozoa from reciprocal translocation carriers.

Human Reproduction, 2013
STUDY QUESTION Is there a relationship between the occurrence of specific segregation modes and the production of additional numerical abnormalities in spermatozoa from reciprocal translocation carriers?
Anna Godo, Joan Blanco, Francesca Vidal, E. Anton   +3 more
semanticscholar   +1 more source

Characteristics and clinical evaluation of X chromosome translocations

Molecular Cytogenetics, 2023
Background Individuals with X chromosomal translocations, variable phenotypes, and a high risk of live birth defects are of interest for scientific study.
Ning Huang, Jihui Zhou, Wan Lu, Laipeng Luo, Huizhen Yuan, Lu Pan, Shujun Ding, Bicheng Yang, Yanqiu Liu   +8 more
doaj   +1 more source

Wheat-barley hybridization – the last forty years [PDF]

, 2013
Several useful alien gene transfers have been reported from related species into wheat (Triticum aestivum), but very few publications have dealt with the development of wheat/barley (Hordeum vulgare) introgression lines. An overview is given here of
A Blanco, A Cabrera, A Cseh, A Cseh, A Farkas, A Kruse, A Löve, A Löve, A Martín, A Martín, A Martín, A Martín, A Martín, A Mujeeb-Kazi, A Mujeeb-Kazi, A Sepsi, AC Martín, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, B Wojciechowska, B Wojciechowska, C Doré, C Nakamura, CC Chu, CH Park, D Bai, D Villegas, DA Kerckhoffs, DJ Allendorf, DR Dewey, E Clauss, E Clauss, ED Nagy, ER Sears, ER Sears, ER Sears, G Fedak, G Fedak, G Fedak, G Fedak, G Fedak, G Fedak, G Fedak, G Galiba, G Kimber, Gabriella Linc, GE Hart, GS Sethi, H Bilgic, H Zou, HC Sharma, I Linde-Laursen, I Schubert, IR Barclay, J Fernandez-Escobar, J Jiang, J Lima-Brito, JA Fernandez, JB Thomas, JD Sherman, JI Cubero, JM Surikov, K Kruppa, K Murai, K Sakai, KC Armstrong, KF Mayer, KFX Mayer, L Junming, L Malysheva, LA Pershina, LA Pershina, LA Pershina, LS Dahleen, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, MD Gale, Márta Molnár-Láng, N Serizawa, P Barcelo, P Suchánková, PJ Larkin, PK Gupta, PP Jauhar, R Bothmer, R Bothmer, R Riley, R Riley, RA Burton, RA Finch, RJ Henry, S Cho, S Griffiths, S Islam, S Nasuda, S Svitashev, S Taketa, S Taketa, S Taketa, S Taketa, SB Chang, T Ashida, T Koba, T Koba, T Schwarzacher, TR Endo, V Chapman, VK Shumny, VK Shumny, Y Ya-Ping, É Szakács, É Szakács, É Szakács, Éva Szakács   +125 more
core   +1 more source

Catastrophic chromosomal restructuring during genome elimination in plants. [PDF]

, 2015
Genome instability is associated with mitotic errors and cancer. This phenomenon can lead to deleterious rearrangements, but also genetic novelty, and many questions regarding its genesis, fate and evolutionary role remain unanswered.
Bradnam, Keith R, Chan, Simon Wl, Comai, Luca, Henry, Isabelle M, Korf, Ian, Lysak, Martin A, Mandakova, Terezie, Marimuthu, Mohan Pa, Ravi, Maruthachalam, Tan, Ek Han   +9 more
core   +1 more source

Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]

, 1990
A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Anna Jauch, Bickmore, Cremer, Cremer, de Grouchy, Dutrillaux, Holmquist, Johannes Wienberg, Lalley, Lichter, Lichter, Lichter, O'Brien, Ohno, Pinkel, Roscoe Stanyon, Seuánez, Stanyon, Thomas Cremer, Van Dilla, Weber, Wienberg, Yunis   +22 more
core   +1 more source

RECIPROCAL TRANSLOCATION IN RICE

The Japanese Journal of Genetics, 1953
Structural change of the chromosomes seems to be little known in the rice plant, though it has been discovered early by Ramiah et al 1935. The writers investigated several semi-sterile strains induced by X-ray irradiation, and recognized their sterility was due to ”reciprocal translocations”. Some genetical and cytological observations of those strains
Hiko-Ichi Oka, M. S. Hong, Te-Tzu Chang
openaire   +4 more sources

Meiosis in two human reciprocal translocations. [PDF]

Journal of Medical Genetics, 1979
Analysis of meiotic chromosomes from two human male translocation heterozygotes is reported. One had total sterility after maturation arrest and chain configurations at meiosis, and the second had a abnormal children who were presumed to be genetically unbalanced.
J.M. García-Sagredo, M.T. Sordo, C S Román   +2 more
openaire   +3 more sources