Results 51 to 60 of about 571 (258)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

IMTKU Textual Entailment System for Recognizing Inference in Text at NTCIR-11 [PDF]

, 2015
In this paper, we describe the IMTKU (Information Management at TamKang University) textual entailment system for recognizing inference in text at NTCIR-11 RITE-VAL (Recognizing Inference in Text). We proposed a textual entailment system using statistics
Day, Min-Yuh, Day, Min-Yuh; Wang, Ya-Jung; Hsu, Che-Wei; Tu, En-Chun; Wu, Shang-Yu; Hsu, Huai-Wen; Lin, Yu-An; Tai, Yu-Hsuan; Tsai, Cheng-Chia, Day, Min-Yuh; Ya-Jung Wang; Che-Wei Hsu; En-Chun Tu; Shang-Yu Wu; Huai-Wen Hsu; Yu-An Lin; Yu-Hsuan Tai; Cheng-Chia Tsai   +2 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Recognizing Textual Entailment Via Atomic Propositions [PDF]

, 2006
This paper describes Macquarie University's Centre for Language Technology contribution to the PASCAL 2005 Recognizing Textual Entailment challenge. Our main aim was to test the practicability of a purely logical approach. For this, atomic propositions were extracted from both the text and the entailment hypothesis and they were expressed in a custom ...
Elena Akhmatova, Diego Mollá
openaire   +1 more source

IMTKU Textual Entailment System for Recognizing Inference in Text at NTCIR-10 RITE-2 [PDF]

, 2013
Min-Yuh Day, Chun Tu, Shih-Jhen Huang, Hou-Cheng Vong, Shih-Wei Wu (2013), "IMTKU Textual Entailment System for Recognizing Inference in Text at NTCIR-10 RITE-2," in Proceedings of the 10th NTCIR Conference on Evaluation of Information Access ...
Day, Min-Yuh; Tu, Chun; Huang, Shih-Jhen; Vong, Hou-Cheng; Wu, Shih-Wei, Min-Yuh Day   +1 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Journal Contribution Recognizing Textual Entailment: A Review of Resource, Approach, and Challenges

, 2023
This is a file journal contribution with the title Recognizing Textual Entailment: A Review of Resource, Approach, and Challenges 
Ahmad Saikhu (14933967), Daniel Siahaan (14933963), I Made Suwija Putra (14759182)   +2 more
core   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

A logic-based semantic approach to recognizing textual entailment [PDF]

Proceedings of the COLING/ACL on Main conference poster sessions -, 2006
This paper proposes a knowledge representation model and a logic proving setting with axioms on demand successfully used for recognizing textual entailments. It also details a lexical inference system which boosts the performance of the deep semantic oriented approach on the RTE data.
Marta Tatu, Dan I. Moldovan
openaire   +2 more sources