Results 81 to 90 of about 12,083 (257)

Recoil Control of Workover Riser System Based on Fuzzy Control Theory

open access: yesShiyou jixie
Workover riser system is a key equipment in workover operation,and accident may occurs during the recoil process after emergency disconnect of it. In order to solve the recoil control problem of workover riser system and reduce the risk in the recoil ...
Wang Jinlong   +6 more
doaj  

Reconfigurable Inflatables Through Controlled Surface Crumpling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflatable structures offer remarkable versatility due to their compact storage and rapid deployment, making them ideal for lightweight, quickly assembled, and deployable applications. These structures are typically made from membranes that are nearly inextensible yet highly flexible.
Yi Yang   +8 more
wiley   +1 more source

Large spatter formation mechanism and its influence on surface quality in additive manufacturing process using in-situ monitoring informed solid–liquid–gas coupling simulation

open access: yesVirtual and Physical Prototyping
Spatter is inherent in laser beam powder bed fusion (PBF-LB), especially large-sized spatter, which is too massive to be effectively removed by the shielding gas flow and thus poses a persistent threat, degrades surface quality.
Xin Lin   +5 more
doaj   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

open access: yesAdvanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li   +4 more
wiley   +1 more source

Numerical study on morphology evolution of restoration crater on fused silica optical surface through low-repetition-rate CO2 pulsed laser

open access: yesCase Studies in Thermal Engineering
This study investigates the CO2 laser-based optical surface restoration mechanism through a multiphase level-set model incorporating solid-liquid-gas phase transitions.
Xiao Shen   +10 more
doaj   +1 more source

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM+ Cholangiocyte Subcluster via Hypoxia/TGF‐β‐CREM‐VIM Axis

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu   +14 more
wiley   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model

open access: yesAdvanced Science, EarlyView.
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble   +9 more
wiley   +1 more source

How Proton Incorporation Reshapes Lattice Dynamics In BaSnO3‐Type Proton Conductors

open access: yesAdvanced Science, EarlyView.
Yttrium‐doped BaSnO3 exhibits isotope‐dependent changes in its low‐energy vibrational density of states upon hydration. Comparison of dry, H2O‐, and D2O‐treated samples re‐veals mass‐dependent phonon renormalization linked to proton dynamics near oxygen va‐cancies, providing experimental insight into hydrogen‐coupled lattice excitations in proton ...
Artur Braun   +9 more
wiley   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao   +11 more
wiley   +1 more source

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