Results 51 to 60 of about 66,901 (296)
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
The aim of the study was to evaluate the effects of diabetes on episodic memory and working memory after controlling for other comorbidities and several demographic and biological variables.
Selene Cansino +5 more
doaj +1 more source
Aristotle’s On Memory and Recollection: Concepts, Sources, and Innovations of Aristotle’s Account of Mnemonic Capacities and Activities [PDF]
My thesis inquires into some of the most relevant problems of Aristotle’s treatise On memory and recollection. The first chapter consists in an analysis of the keywords of the work.
MEDDA, ROBERTO
core
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Do young children, like young adults, remember animates better than inanimates?
It has repeatedly been shown in adults that animates are remembered better than inanimates. According to the adaptive view of human memory this is due to the fact that animates are generally more important for survival than inanimates.
Aurélia Bugaiska +2 more
doaj +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Multiple Exposures Enhance Both Item Memory and Contextual Memory Over Time
Repetition learning is an efficient way to enhance memory performance in our daily lives and educational practice. However, it is unclear to what extent repetition or multiple exposures modulate different types of memory over time.
Haoyu Chen +3 more
doaj +1 more source
Examining the relationship between processing fluency and memory for source information
Familiarity-based processes such as processing fluency can influence memory judgements in tests of item recognition. Many conventional accounts of source memory assume minimal influence of familiarity on source memory, but recent work has suggested that ...
Tina S.-T. Huang, David R. Shanks
doaj +1 more source

