Results 1 to 10 of about 317,082 (116)

Retrosplenial cortex 5-HT2A receptors critically contribute to recognition memory processing [PDF]

Frontiers in Cellular Neuroscience
The anterior retrosplenial cortex (aRSC) functions as a hub that integrates multimodal sensory inputs into associative recognition memories. Although the aRSC receives dense serotonergic projections from the raphe nuclei, the role of serotonin in its ...
Beatriz Agustina Ortega, Beatriz Agustina Ortega, Noelia V. Weisstaub, Noelia V. Weisstaub, Cynthia Katche, Cynthia Katche   +5 more
doaj   +2 more sources

Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism

BMC Neuroscience, 2021
Background Autism spectrum disorder (ASD) is characterized by the core symptoms of impaired social interactions. Increasing evidence suggests that ASD has a strong genetic link with mutations in chromodomain helicase DNA binding protein 8 (CHD8), a gene ...
Stanislav M. Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I. Nakayama, Masaaki Nishiyama, Haruhiro Higashida   +8 more
doaj   +1 more source

Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside

Frontiers in Neuroscience, 2022
Investigating the neurocircuit and synaptic sites of action of oxytocin (OT) in the brain is critical to the role of OT in social memory and behavior.
Haruhiro Higashida, Haruhiro Higashida, Kazumi Furuhara, Olga Lopatina, Olga Lopatina, Maria Gerasimenko, Osamu Hori, Tsuyoshi Hattori, Yasuhiko Hayashi, Stanislav M. Cherepanov, Anna A. Shabalova, Alla B. Salmina, Alla B. Salmina, Kana Minami, Teruko Yuhi, Chiharu Tsuji, PinYue Fu, Zhongyu Liu, Shuxin Luo, Anpei Zhang, Shigeru Yokoyama, Satoshi Shuto, Mizuki Watanabe, Koichi Fujiwara, Sei-ichi Munesue, Ai Harashima, Yasuhiko Yamamoto   +26 more
doaj   +1 more source

Receptor for advanced glycation end-products and child neglect in mice: A possible link to postpartum depression

Comprehensive Psychoneuroendocrinology, 2022
The receptor for advanced glycation end-products (RAGE), a pattern recognition molecule, has a role in the remodeling of vascular endothelial cells mainly in lungs, kidney and brain under pathological conditions.
Haruhiro Higashida, Maria Gerasimenko, Yasuhiko Yamamoto   +2 more
doaj   +1 more source

Threshold models of recognition and the recognition heuristic [PDF]

Judgment and Decision Making, 2011
According to the recognition heuristic (RH) theory, decisions follow the recognition principle: Given a high validity of the recognition cue, people should prefer recognized choice options compared to unrecognized ones.
Edgar Erdfelder, Carolina E. Küpper-Tetzel, Sandra D. Mattern, Julian N. Marewski, Rüdiger F. Pohl, Oliver Vitouch   +5 more
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Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder

Scientific Reports, 2020
Oxytocin (OT) is a critical molecule for social recognition and memory that mediates social and emotional behaviours. In addition, OT acts as an anxiolytic factor and is released during stress. Based on the activity of CD38 as an enzyme that produces the
Maria Gerasimenko, Stanislav M. Cherepanov, Kazumi Furuhara, Olga Lopatina, Alla B. Salmina, Anna A. Shabalova, Chiharu Tsuji, Shigeru Yokoyama, Katsuhiko Ishihara, Charles Brenner, Haruhiro Higashida   +10 more
doaj   +1 more source

One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates with Autism Spectrum Disorder in a Japanese Population

Diseases, 2020
The transient receptor potential melastatin 2 (TRPM2) is a non-specific cation channel, resulting in Ca2+ influx at warm temperatures from 34 °C to 47 °C, thus including the body temperature range in mammals.
Naila Al Mahmuda, Shigeru Yokoyama, Toshio Munesue, Kenshi Hayashi, Kunimasa Yagi, Chiharu Tsuji, Haruhiro Higashida   +6 more
doaj   +1 more source

Cholinergic regulation of object recognition memory

Frontiers in Behavioral Neuroscience, 2022
Object recognition memory refers to a basic memory mechanism to identify and recall various features of objects. This memory has been investigated by numerous studies in human, primates and rodents to elucidate the neuropsychological underpinnings in ...
Kana Okada, Kouichi Hashimoto, Kazuto Kobayashi   +2 more
doaj   +1 more source

Verbal Encoding Deficits Impact Recognition Memory in Atypical “Non-Amnestic” Alzheimer’s Disease

Brain Sciences, 2022
Memory encoding and retrieval deficits have been identified in atypical Alzheimer’s disease (AD), including posterior cortical atrophy (PCA) and logopenic variant primary progressive aphasia (lvPPA), despite these groups being referred to as “non ...
Deepti Putcha, Nicole Carvalho, Sheena Dev, Scott M. McGinnis, Bradford C. Dickerson, Bonnie Wong   +5 more
doaj   +1 more source

Saccades and handedness interact to affect scene memory [PDF]

PeerJ, 2018
Repetitive saccades benefit memory when executed before retrieval, with greatest effects for episodic memory in consistent-handers. Questions remain including how saccades affect scene memory, an important visual component of episodic memory. The present
Timothy M. Ellmore, Bridget Mackin, Kenneth Ng   +2 more
doaj   +2 more sources