Results 21 to 30 of about 1,401,477 (306)

Selegiline Ameliorates Depression-Like Behavior in Mice Lacking the CD157/BST1 Gene, a Risk Factor for Parkinson’s Disease

Frontiers in Behavioral Neuroscience, 2017
Parkinson’s disease (PD), a neurodegenerative disorder, is accompanied by various non-motor symptoms including depression and anxiety, which may precede the onset of motor symptoms. Selegiline is an irreversible monoamine oxidase-B (MAO-B) inhibitor, and
Satoka Kasai, Satoka Kasai, Toru Yoshihara, Toru Yoshihara, Olga Lopatina, Katsuhiko Ishihara, Haruhiro Higashida   +6 more
doaj   +1 more source

Nicotine enhances object recognition memory through inhibition of voltage-dependent potassium 7 channels in the medial prefrontal cortex of mice

Journal of Pharmacological Sciences, 2021
Nicotine administration enhances object recognition memory. However, target brain regions and cellular mechanisms underlying the nicotine effects remain unclear.
Hirohito Esaki, Shoma Izumi, Akari Fukao, Naoya Nishitani, Satoshi Deyama, Katsuyuki Kaneda   +5 more
doaj   +1 more source

Spatial memory, recognition memory, and the hippocampus [PDF]

Proceedings of the National Academy of Sciences, 2004
There is wide agreement that spatial memory is dependent on the integrity of the hippocampus, but the importance of the hippocampus for nonspatial tasks, including tasks of object recognition memory is not as clear. We examined the relationship between hippocampal lesion size and both spatial memory and object recognition memory in rats. Spatial memory
Nicola J, Broadbent, Larry R, Squire, Robert E, Clark   +2 more
openaire   +2 more sources

Medial temporal lobe contributions to intra-item associative recognition memory in the aging brain [PDF]

, 2014
Aging is associated with a decline in episodic memory function. This is accompanied by degradation of and functional changes in the medial temporal lobe (MTL) which subserves mnemonic processing.
John Russel Hodges, John Russel Hodges, John Russel Hodges, Marshall Axel Dalton, Marshall Axel Dalton, Marshall Axel Dalton, Michael eHornberger, Michael eHornberger, Michael eHornberger, Olivier ePiguet, Olivier ePiguet, Olivier ePiguet, Sicong eTu, Sicong eTu, Sicong eTu   +14 more
core   +2 more sources

CD38, CD157, and RAGE as Molecular Determinants for Social Behavior

Cells, 2019
Recent studies provide evidence to support that cluster of differentiation 38 (CD38) and CD157 meaningfully act in the brain as neuroregulators. They primarily affect social behaviors. Social behaviors are impaired in Cd38 and Cd157 knockout mice. Single-
Haruhiro Higashida, Minako Hashii, Yukie Tanaka, Shigeru Matsukawa, Yoshihiro Higuchi, Ryosuke Gabata, Makoto Tsubomoto, Noriko Seishima, Mitsuyo Teramachi, Taiki Kamijima, Tsuyoshi Hattori, Osamu Hori, Chiharu Tsuji, Stanislav M. Cherepanov, Anna A. Shabalova, Maria Gerasimenko, Kana Minami, Shigeru Yokoyama, Sei-ichi Munesue, Ai Harashima, Yasuhiko Yamamoto, Alla B. Salmina, Olga Lopatina   +22 more
doaj   +1 more source

Dopamine activity on the perceptual salience for recognition memory

Frontiers in Behavioral Neuroscience, 2022
To survive, animals must recognize relevant stimuli and distinguish them from inconspicuous information. Usually, the properties of the stimuli, such as intensity, duration, frequency, and novelty, among others, determine the salience of the stimulus ...
Daniel Osorio-Gómez, Kioko Guzmán-Ramos, Federico Bermúdez-Rattoni   +2 more
doaj   +1 more source

Intestinal transepithelial permeability of oxytocin into the blood is dependent on the receptor for advanced glycation end products in mice

Scientific Reports, 2017
Plasma oxytocin (OT) originates from secretion from the pituitary gland into the circulation and from absorption of OT in mother’s milk into the blood via intestinal permeability.
Haruhiro Higashida, Kazumi Furuhara, Agnes-Mikiko Yamauchi, Kisaburo Deguchi, Ai Harashima, Seiichi Munesue, Olga Lopatina, Maria Gerasimenko, Alla B. Salmina, Jia-Sheng Zhang, Hikari Kodama, Hironori Kuroda, Chiharu Tsuji, Satoshi Suto, Hiroshi Yamamoto, Yasuhiko Yamamoto   +15 more
doaj   +1 more source

A single-system model predicts recognition memory and repetition priming in amnesia [PDF]

, 2014
We challenge the claim that there are distinct neural systems for explicit and implicit memory by demonstrating that a formal single-system model predicts the pattern of recognition memory (explicit) and repetition priming (implicit) in amnesia.
Berry, CJ, Kessels, RPC, Shanks, DR, Wester, AJ   +3 more
core   +5 more sources

Transcutaneous vagus nerve stimulation does not affect verbal memory performance in healthy volunteers [PDF]

, 2020
Introduction: Invasive vagus nerve stimulation (VNS) improves word recognition memory in patients with epilepsy. Recent studies with transcutaneous VNS (tVNS) have also shown positive effects on various subdomains of cognitive functioning in healthy ...
Boon, Paul, Carrette, Evelien, Gadeyne, Stefanie, Mertens, Ann, Miatton, Marijke, Naert, Lien, Poppa, Tasha, Raedt, Robrecht, Vonck, Kristl   +8 more
core   +1 more source

Android Robot-Mediated Mock Job Interview Sessions for Young Adults with Autism Spectrum Disorder: A Pilot Study

Frontiers in Psychiatry, 2017
The feasibility and preliminary efficacy of an android robot-mediated mock job interview training in terms of both bolstering self-confidence and reducing biological levels of stress in comparison to a psycho-educational approach human interview was ...
Hirokazu Kumazaki, Zachary Warren, Blythe A. Corbett, Yuichiro Yoshikawa, Yuichiro Yoshikawa, Yoshio Matsumoto, Haruhiro Higashida, Teruko Yuhi, Takashi Ikeda, Hiroshi Ishiguro, Hiroshi Ishiguro, Mitsuru Kikuchi   +11 more
doaj   +1 more source