Results 141 to 150 of about 892,210 (336)

Poly(ADP-Ribosyl)ation affects stabilization of CHE-1 protein in response to DNA damage [PDF]

open access: yes, 2011
Post-translation modifications play a crucial role in coordinating the cellular response to DNA damage. Double strand DNA breaks (DSBs) trigger the activation of ATM and Chk2 kinases, which represent the primary transducers in the signalling cascade ...
BACALINI, MARIA GIULIA
core  

Harnessing Non‐Covalent Protein–Protein Interaction Domains for Production of Biocatalytic Materials Systems

open access: yesAdvanced Functional Materials, EarlyView.
Non‐covalent protein–protein interactions mediated by SH3, PDZ, or GBD domains enable the self‐assembly of stable and biocatalytically active hydrogel materials. These soft materials can be processed into monodisperse foams that, once dried, exhibit enhanced mechanical stability and activity and are easily integrated into microstructured flow ...
Julian S. Hertel   +5 more
wiley   +1 more source

Bioinspired Design of a Wet‐Adhesive Cornea Glue Based on Recombinant Human Protein Networks

open access: yesAdvanced Functional Materials, EarlyView.
Natures protein‐based high performance materials e.g. elastin, silk and muscle proteins have been mimicked by a new protein‐hybrid material based on redesigned human partial sequences only, showing high wet‐adhesiveness and elasticity for biomedical applications.
Anna Resch   +17 more
wiley   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak   +6 more
wiley   +1 more source

Construction and Immunogenicity Testing of Salmonella, STM1 Vaccine Vector Expressing HIV-1 Antigen

open access: yesIndonesian Journal of Biotechnology, 2015
Objective of this study: to determine the ability of Salmonella enterica serovar Typhimurium STM1 as a delivery vehicle for the HIV p24 gene and HIV env gene.
Endang Winiati Bachtiar   +2 more
doaj  

A Twist in the Diagnosis: Chronic Arthropathy Without Inflammation

open access: yes
Arthritis Care &Research, EarlyView.
María Á. Puche‐Larrubia   +3 more
wiley   +1 more source

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret   +4 more
wiley   +1 more source

Designing and Construction of Recombinant Plasmid Consisting of Basic Fibroblast Growth Factor and Immunodominant Fragments of Pseudomonas Exotoxin

open access: yesMedical Laboratory Journal, 2015
Background and Objective: the inhibition of tumor-associated angiogenesis can significantly reduce the tumor proliferation. The basic fibroblast growth factor (bFGF), an important angiogenic factor, is considered as a potential therapeutic target for ...
H Haghighatfard, Y Yazdani, Y.
doaj  

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