Results 261 to 270 of about 3,228,085 (398)
Arf1 defects activate the AKT‐mTORC1‐SREBP1‐FASN pathway to increase lipid synthesis and disrupt ER‐mitochondrial‐lysosomal homeostasis in neurons. Impaired mitochondria secrete damaged mtDNA via mitochondria‐derived extracellular vesicles, which is phagocytosed by the microglia and activated inflammation signaling.
Xu Li+10 more
wiley +1 more source
Generation of an artificially attenuated fowl adenovirus 4 viral vector using the reverse genetics system based on full-length infectious clone. [PDF]
Tang Z, Feng D, Fan W, Yan L, Song S.
europepmc +1 more source
SAFETY AND EFFICACY OF A RECOMBINANT DNA PLASMODIUM FALCIPARUM SPOROZOITE VACCINE
W. Ripley Ballou+13 more
openalex +1 more source
Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis [PDF]
Kazuhiko Igarashi+3 more
openalex +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan+12 more
wiley +1 more source
Recombinant DNA Hepatitis B Vaccination in Teenagers: Effect of a Booster at 51/2 Years [PDF]
A Milne, John Waldon
openalex +1 more source