Assessing diagnostic, vaccine and therapeutic potential of selected <i>Trichinella</i> proteins. [PDF]
Stachyra A, Bień-Kalinowska J.
europepmc +1 more source
Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang +10 more
wiley +1 more source
Recombinant ROP6 protein expressed in Saccharomyces cerevisiae INVSc1 cells induced strong immune response and provided significant protection against toxoplasmosis. [PDF]
Karakavuk T +17 more
europepmc +1 more source
A Novel Recombinant DNA System for High Efficiency Affinity Purification of Proteins in Saccharomyces cerevisiae. [PDF]
Carrick BH +3 more
europepmc +1 more source
Inhibition of RNase to Attenuate Fungal‐Manipulated Rhizosphere Microbiome and Diseases
Fusarium graminearum uses its virulence effector Fg12, a fungal RNase, to manipulate the host rhizosphere microbiome and promote infection. Guanosine monophosphate (GMP) blocks Fg12's RNase activity. This reveals a key pathogen‐microbiota interaction mechanism and proposes GMP as a targeted strategy to disarm this core fungal effector, offering a ...
Bo Yang +13 more
wiley +1 more source
Construction and optimization of a nisin-controlled expression vector using a pre-screened strong promoter in <i>Streptococcus thermophilus</i>. [PDF]
Ye Y, Zhao R, Li L, Li Z, Chen Y, Xu Z.
europepmc +1 more source
Researchers have identified a citrus chimera with distinctive tissue origins and carotenoid profiles. It is discovered that fruit tissues develop from all three cell layers but in different proportions. A key transcription factor, MYB107, regulates β‐cryptoxanthin production by directly activating carotenoid biosynthesis genes, explaining why some ...
Chi Zhang +8 more
wiley +1 more source
A novel feline herpesvirus vector subunit FCV VP1 and FPV VP2 vaccine protects cats against FHV-1 and FPV challenge and induces serum neutralizing antibody responses against FCV. [PDF]
Tang A +11 more
europepmc +1 more source

