Results 291 to 300 of about 892,210 (336)

An Autographa californica multiple nucleopolyhedrovirus-encoded microRNA, AcMNPV-miR-5, downregulates the expression of viral gene <i>ac66</i>. [PDF]

J Gen Virol
Teng T, Duan Z, Li A, Wang J.
europepmc   +1 more source

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

Advanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li, Jinlin Liao, Yuxi Zhang, Zifu Yao, Junxin Huang, Kejia Wu, Lu Li, Yiling Peng, Haili Zhu, Xue Hong, Xi Liu, Lili Zhou, Fan Fan Hou, Haiyan Fu, Youhua Liu   +14 more
wiley   +1 more source

Outer membrane vesicles from <i>Escherichia coli</i> as a presentation platform for AR-23 antiviral peptide. [PDF]

Front Mol Biosci
Mensitieri F, Dell'Annunziata F, Gaudino G, Folliero V, Franci G, Dal Piaz F, Izzo V.   +6 more
europepmc   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Production of recombinant human G protein-coupled estrogen receptor (GPER) and establishment of a ligand binding assay using graphene quantum dots (GQDs). [PDF]

PLoS One
Hossain S, Hossain MF, Sohan MSR, Omori Y, Amin MT, Tokumoto T.   +5 more
europepmc   +1 more source

Efficient extracellular expression and rapid screening of human-like recombinant gelatin in Komagataella phaffii. [PDF]

Sci Rep
Song X, Wang Y, Kan K, Chai Z, Wang L, Li M, Liu Z.   +6 more
europepmc   +1 more source

Insect cell expression system: advances in applications, engineering strategies, and bioprocess development. [PDF]

J Biol Eng
Huang N, Wei Y, Li J.
europepmc   +1 more source

Highly efficient gene editing of <i>Feline herpesvirus 1</i> using CRISPR/Cas9 combined with FACS. [PDF]

Front Cell Infect Microbiol
Wang HM, Xu SJ, Cai BY, Qiu WY, Lu H, Tang YD.   +5 more
europepmc   +1 more source

Robotics for recombinant DNA and human genetics research

, 1990
Tony J. Beugelsdijk
openalex   +1 more source

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RECOMBINANT DNA TECHNOLOGY

The Lancet, 1981
Publisher Summary Plasmids are widely used as vectors and methods of their isolation can vary depending upon the host organism. On the basis of phenotypic effect and organization in the chromosomes, genes can be subdivided into various groups, such as simple genes, complex genes, operons, regulons, and multiple regulons.
openaire   +6 more sources