Results 111 to 120 of about 13,664 (205)

TREATMENT OF HEMOPHILIA WITH HUMAN FACTORIX PRODUCED IN MAMIMARY TISSUE OF TRANSGENIC MAMMALS [PDF]

, 2008
Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention.
Drohan, William N., Johnson, John L., Johnson, Mary Ann H., Lubon, Henryk, Velander, William H.   +4 more
core   +1 more source

Off-label use of recombinant factor VIIa for neonatal pulmonary hemorrhage; a single-center experience

The Turkish Journal of Pediatrics
Background. Pulmonary hemorrhage (PH) leads to acute and catastrophic deterioration in neonates, and there is no curative treatment available. Off-label use of recombinant Factor VIIa (rFVIIa) is a promising treatment to control bleeding.
Özge Serçe Pehlevan, Ayna Atayeva, Ayla Günlemez, Sibel Balcı   +3 more
doaj   +1 more source

Successful Desensitization Protocol in an Infant Following Anaphylaxis Secondary to Recombinant Factor VIIa. [PDF]

Pediatr Allergy Immunol Pulmonol, 2020
Ulusoy Severcan E, Cigerci Gunaydin N, Hekimci Ozdemir H, Gulen F, Kavakli K, Tanac R, Demir E.   +6 more
europepmc   +1 more source

Glanzmann’s thrombasthenia: A nightmare for hernia surgeons

Journal of Minimal Access Surgery
Glanzmann’s thrombasthenia is a rare inherited disorder affecting one in one million. It is characterised by a lack of platelet aggregation due to a defect in the platelet membrane receptor complex (αIIb/βIIIa), which mediates the aggregation of ...
Jignesh Gandhi, Aarsh Gajjar, Pravin Shinde, Yogesh Takalkar   +3 more
doaj   +1 more source

Therapeutic doses of recombinant factor VIIa in hemophilia generates thrombin in platelet-dependent and -independent mechanisms. [PDF]

J Thromb Haemost, 2020
Keshava S, Pendurthi UR, Esmon CT, Rao LVM.   +3 more
europepmc   +1 more source

Updates in perioperative coagulation: physiology and management of thromboembolism and haemorrhage [PDF]

, 2017
Understanding of blood coagulation has evolved significantly in recent years. Both new coagulation proteins and inhibitors have been found and new interactions among previously known components of the coagulation system have been discovered.
Bombeli, T., Spahn, D. R.
core  

The Coagulation Box and a New Hemoglobin-Driven Algorithm for Bleeding Control in Patients with Severe Multiple Traumas [PDF]

, 2013
Background: Extensive hemorrhage is the leading cause of death in the first few hours following multiple traumas. Therefore, early and aggressive treatment of clotting disorders could reduce mortality.
Hilbert, P., Hofmann, G.O., Struck, M.F., Stuttmann, R., Teichmann, J.   +4 more
core  

Use of Low-Dose Recombinant Factor Ⅶa for Uncontrolled Perioperative Bleeding. [PDF]

Dose Response, 2020
Chang ZG, Chu X, Chen W, Hu JH, Gong JW, Liu DD, He Q, Feng Z, Xiao SR, Liu YL.   +9 more
europepmc   +1 more source

Antithrombotic and hemostatic stewardship: evaluation of clinical outcomes and adverse events of recombinant factor VIIa (Novoseven^®) utilization at a large academic medical center. [PDF]

Ther Adv Cardiovasc Dis, 2020
Marsh K, Green D, Raco V, Papadopoulos J, Ahuja T.   +4 more
europepmc   +1 more source

Hematuria Status Post Renal Biopsy [PDF]

, 2012
This is a case of a 66 year old Caucasian woman admitted to the hospital following a ureteroscopic biopsy of the left renal pelvis. The biopsy was performed for asymptomatic hematuria, with a retrograde intravenous pyelogram revealing a mass in the left ...
McElhaugh, Bill
core   +1 more source