Results 61 to 70 of about 13,664 (205)
Successful Vaginal Delivery in a Pregnant Woman With Bernard–Soulier Syndrome: A Case Report
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Bernard–Soulier syndrome (BSS) is a rare inherited platelet disorder that poses major risks during pregnancy because of potential bleeding complications. Managing such cases in low‐resource settings is especially challenging. We report the case of a 23‐year‐old Afghan woman with BSS who achieved a successful full‐term vaginal delivery at a ...
Monireh Yaghoubi +2 more
wiley +1 more source
Recent acquisitions in the pathophysiology, diagnosis and treatment of disseminated intravascular coagulation [PDF]
, 2006 Disseminated intravascular coagulation (DIC) is a disorder characterized by both acute generalized, widespread activation of coagulation, which results in thrombotic complications due to the intravascular formation of fibrin, and diffuse hemorrhages, due
Lippi Giuseppe +2 more
core +2 more sources
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay +4 more
wiley +1 more source
Pediatric cardiac surgery under cardiopulmonary bypass in factor VII deficiency
The Turkish Journal of Pediatrics, 2010 We present a case of an atrial septal defect repair under cardiopulmonary bypass in a child with factor VII deficiency. A four-year-old girl, with the diagnosis of secundum atrial septal defect, was referred to surgery. Coagulation tests showed an
Ozan Emiroğlu +3 more
doaj
Acquired Hemophilia A Presenting as Intramuscular Hematoma
Journal of Investigative Medicine High Impact Case Reports, 2018 Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma
Ghassan Al-Shbool MD, Anusha Vakiti MD
doaj +1 more source
Turkish Journal of Hematology, 2015 Invasive fungal infections have turned out to be a significant cause of morbidity and mortality in pediatric patients with malignant disorders. Massive hemoptysis, a rare complication of invasive pulmonary aspergillosis, may threaten the lives of ...
Dilek Gürlek Gökçebay +4 more
doaj +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 1, January 2026.ABSTRACT Background Hemophilia A (HA) is a rare bleeding disorder caused by coagulation factor VIII (FVIII) deficiency. Prophylactic FVIII replacement therapy is essential for preventing bleeds, but it carries a risk of inhibitor development, especially in previously untreated and minimally treated patients (PUPs and MTPs, respectively).
Sarina Levy‐Mendelovich +11 more
wiley +1 more source
HEMOPHILIA INHIBITOR PATIENTS: THE USE OF RECOMBINANT FACTOR VIIa
Zdravniški Vestnik, 2004 Background. Recombinant factor VIIa can induce hemostasis and controls bleeding in surgery in hemophilia inhibitor patients and in other hemostatic disorders, e.g.
Dušan Andoljšek, Samo Zver
doaj
Tissue factor in cardiovascular disease pathophysiology and pharmacological intervention [PDF]
, 2010 Tissue factor (TF) is the major trigger of the coagulation cascade and thereby crucially involved in the maintenance of vascular hemostasis. By binding factor VIIa, the resulting TF:VIIa complex activates the coagulation factors IX and X ultimately ...
Holy, E W, Tanner, F C
core +1 more source
Case Reports in Pediatrics, Volume 2026, Issue 1, 2026.Systemic lupus erythematosus (SLE) is a rare autoimmune disorder, rarely presenting with central nervous system (CNS) hemorrhage—especially cerebellar involvement. We report a previously healthy 17‐year‐old female presenting with severe thrombocytopenia and cerebellar hemorrhage, leading to a diagnosis of SLE.
Bosaina Otour +6 more
wiley +1 more source